STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN88744.1D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.980
KRN88944.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.980
KRN89134.1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.934
KRN89534.1
Acetolactate synthase; Belongs to the TPP enzyme family.
  
 
 0.924
KRN89385.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 
 0.921
KRN88927.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.918
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
  0.917
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.838
KRN88743.1
Hypothetical protein.
       0.719
KRN88742.1
O-methyltransferase.
       0.703
Your Current Organism:
Lactobacillus ceti
NCBI taxonomy Id: 1122146
Other names: L. ceti DSM 22408, Lactobacillus ceti 142-2, Lactobacillus ceti DSM 22408
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.