STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN89534.1Acetolactate synthase; Belongs to the TPP enzyme family. (559 aa)    
Predicted Functional Partners:
KRN89535.1
Alpha-acetolactate decarboxylase.
 
 
 0.999
KRN88944.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.961
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.949
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.948
KRN89134.1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.940
KRN90001.1
Pta protein.
  
 
 0.940
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.933
KRN89385.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 
 0.929
KRN88744.1
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.924
KRN88927.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.924
Your Current Organism:
Lactobacillus ceti
NCBI taxonomy Id: 1122146
Other names: L. ceti DSM 22408, Lactobacillus ceti 142-2, Lactobacillus ceti DSM 22408
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.