STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFLysylphosphatidylglycerol synthetase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (331 aa)    
Predicted Functional Partners:
KRM56738.1
Glycosyltransferase.
 
  
 0.898
KRM56739.1
Glycosyltransferase.
 
  
 0.826
KRM56736.1
Phosphoglycerol transferase alkaline phosphatase superfamily protein.
  
    0.659
KRM57196.1
Hypothetical protein.
  
     0.634
KRM58760.1
Hemolysin-like protein.
  
     0.627
KRM59030.1
Hypothetical protein.
  
     0.618
KRM56735.1
Phosphoglycerol transferase alkaline phosphatase superfamily protein.
 
    0.568
KRM60065.1
Hypothetical protein.
  
     0.566
KRM60038.1
Hypothetical protein.
  
     0.519
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.513
Your Current Organism:
Lactobacillus malefermentans
NCBI taxonomy Id: 1122149
Other names: L. malefermentans DSM 5705 = KCTC 3548, Lactobacillus malefermentans DSM 5705, Lactobacillus malefermentans DSM 5705 = KCTC 3548, Lactobacillus malefermentans KCTC 3548, Lactobacillus malefermentans KCTC 3548 = DSM 5705
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.