SHF26948.1 protein (Lactonifactor longoviformis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SHF26948.1

Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family. (838 aa)

Predicted Functional Partners:

SHF51500.1

0.876

SHE85961.1

0.782

SHF47620.1

0.778

SHF26927.1

0.757

SHF25091.1

0.743

SHE96880.1

0.737

SHE62890.1

0.689

SHF46992.1

0.684

SHF47160.1

0.684

SHE46150.1

0.677

Your Current Organism:

Lactonifactor longoviformis

NCBI taxonomy Id: 1122155
Other names: L. longoviformis DSM 17459, Lactonifactor longoviformis DSM 17459

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHE46150.1	SHF25091.1	SAMN02745158_00521	SAMN02745158_03027	Glucan-binding domain-containing protein (YG repeat).	Beta-xylosidase, GH43 family.	0.699
SHE46150.1	SHF26948.1	SAMN02745158_00521	SAMN02745158_03090	Glucan-binding domain-containing protein (YG repeat).	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.677
SHE46150.1	SHF47620.1	SAMN02745158_00521	SAMN02745158_03888	Glucan-binding domain-containing protein (YG repeat).	Uncharacterized protein, contains GBA2_N and DUF608 domains.	0.527
SHE62890.1	SHF25091.1	SAMN02745158_01082	SAMN02745158_03027	Glucan-binding domain-containing protein (YG repeat).	Beta-xylosidase, GH43 family.	0.700
SHE62890.1	SHF26948.1	SAMN02745158_01082	SAMN02745158_03090	Glucan-binding domain-containing protein (YG repeat).	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.689
SHE62890.1	SHF47620.1	SAMN02745158_01082	SAMN02745158_03888	Glucan-binding domain-containing protein (YG repeat).	Uncharacterized protein, contains GBA2_N and DUF608 domains.	0.527
SHE85961.1	SHE96880.1	SAMN02745158_01785	SAMN02745158_02134	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	0.777
SHE85961.1	SHF26948.1	SAMN02745158_01785	SAMN02745158_03090	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.782
SHE96880.1	SHE85961.1	SAMN02745158_02134	SAMN02745158_01785	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	0.777
SHE96880.1	SHF26948.1	SAMN02745158_02134	SAMN02745158_03090	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.737
SHE96880.1	SHF51500.1	SAMN02745158_02134	SAMN02745158_04040	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	YhcH/YjgK/YiaL family protein.	0.475
SHF25091.1	SHE46150.1	SAMN02745158_03027	SAMN02745158_00521	Beta-xylosidase, GH43 family.	Glucan-binding domain-containing protein (YG repeat).	0.699
SHF25091.1	SHE62890.1	SAMN02745158_03027	SAMN02745158_01082	Beta-xylosidase, GH43 family.	Glucan-binding domain-containing protein (YG repeat).	0.700
SHF25091.1	SHF26948.1	SAMN02745158_03027	SAMN02745158_03090	Beta-xylosidase, GH43 family.	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.743
SHF26927.1	SHF26948.1	SAMN02745158_03089	SAMN02745158_03090	D-lyxose ketol-isomerase.	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	0.757
SHF26948.1	SHE46150.1	SAMN02745158_03090	SAMN02745158_00521	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	Glucan-binding domain-containing protein (YG repeat).	0.677
SHF26948.1	SHE62890.1	SAMN02745158_03090	SAMN02745158_01082	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	Glucan-binding domain-containing protein (YG repeat).	0.689
SHF26948.1	SHE85961.1	SAMN02745158_03090	SAMN02745158_01785	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	0.782
SHF26948.1	SHE96880.1	SAMN02745158_03090	SAMN02745158_02134	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	0.737
SHF26948.1	SHF25091.1	SAMN02745158_03090	SAMN02745158_03027	Beta-mannosidase; Belongs to the glycosyl hydrolase 2 family.	Beta-xylosidase, GH43 family.	0.743

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Network Stats

number of nodes:

7

number of edges:

12

average node degree:

3.43

avg. local clustering coefficient:

0.795

expected number of edges:

6

PPI enrichment p-value:

0.0245

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

11 of 17

2.59

11.22

6.40e-25

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 5

2.38

1.38

0.0028

GO:0005524

ATP binding

5 of 481

0.8

0.49

0.0253

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

11 of 17

2.59

11.48

1.35e-25

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

6 of 10

2.56

6.26

3.31e-13

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

5 of 7

2.63

5.43

3.04e-11

GO:0031676

Plasma membrane-derived thylakoid membrane

11 of 123

1.73

4.67

8.61e-18

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1123

Proton channel activity

11 of 18

2.57

10.94

1.75e-24

CL:1125

ATP synthesis

10 of 13

2.67

10.51

1.91e-22

CL:1126

ATP synthesis

6 of 7

2.71

6.17

1.31e-12

CL:1139

ATP synthesis

4 of 6

2.6

3.61

1.46e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00195

Photosynthesis

11 of 80

1.92

5.98

2.32e-19

map00190

Oxidative phosphorylation

11 of 88

1.88

5.72

3.09e-19

map01100

Metabolic pathways

11 of 2083

0.5

0.43

0.00014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

11 of 18

2.57

11.19

3.96e-25

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

6 of 10

2.56

5.87

2.41e-12

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

5 of 8

2.58

4.92

2.85e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0066

ATP synthesis

11 of 16

2.62

11.63

1.10e-25

KW-0375

Hydrogen ion transport

11 of 19

2.54

11.16

2.29e-25

KW-0139

CF(1)

6 of 9

2.6

6.16

7.38e-13

KW-0138

CF(0)

5 of 7

2.63

5.17

1.10e-10

KW-0793

Thylakoid

11 of 108

1.79

5.07

2.21e-18

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00430

ATP synthase B/B CF(0)

3 of 3

2.78

2.32

5.65e-05

PF00231

ATP synthase

2 of 2

2.78

1.22

0.0062

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 4

2.48

1.08

0.0104

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