STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lsha_0563Putative thiol-disulfide isomerase. (185 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
      0.722
enhB_2
Enhanced entry protein EnhB.
       0.561
Lsha_2234
Cytochrome C biogenesis protein.
  
  
 0.526
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.521
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.507
lysAC_2
Bifunctional aspartate kinase/diaminopimelate decarboxylase protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
  0.482
lidK
(CDP-alcohol) phosphatidyltransferase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.455
cysK
Cystathionine beta synthase.
   
 
 0.428
Your Current Organism:
Legionella shakespearei
NCBI taxonomy Id: 1122169
Other names: L. shakespearei DSM 23087, Legionella shakespearei ATCC 49655, Legionella shakespearei CCUG 31228A, Legionella shakespearei DSM 23087, Legionella shakespearei NCTC 12829
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