STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa)    
Predicted Functional Partners:
SHJ11815.1
Methionine synthase (B12-dependent).
  
 
 0.954
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.903
SHJ88914.1
methylmalonyl-CoA mutase C-terminal domain-containing protein.
  
 
 0.900
SHJ69633.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.899
SHI75623.1
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid).
   
 0.891
SHI81937.1
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
    
 0.887
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.885
SHI46808.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.878
SHI50502.1
Nucleoside-diphosphate-sugar epimerase.
   
 0.875
SHI76165.1
UDP-glucose 4-epimerase.
   
 0.875
Your Current Organism:
Malonomonas rubra
NCBI taxonomy Id: 1122189
Other names: M. rubra DSM 5091, Malonomonas rubra DSM 5091
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.