SJZ59825.1 protein (Marinactinospora thermotolerans)

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SJZ59825.1

2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (294 aa)

Predicted Functional Partners:

SKA02021.1

0.828

SJZ55477.1

0.773

fumC

0.773

SKA32877.1

0.757

SKA19973.1

0.726

SJZ59792.1

0.701

SJZ59771.1

0.649

SKA32875.1

0.632

SKA32909.1

0.632

SKA32869.1

0.622

Your Current Organism:

Marinactinospora thermotolerans

NCBI taxonomy Id: 1122192
Other names: M. thermotolerans DSM 45154, Marinactinospora thermotolerans DSM 45154

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SJZ55477.1	SJZ59825.1	SAMN02745673_00728	SAMN02745673_00872	Malate synthase; Belongs to the malate synthase family.	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	0.773
SJZ55477.1	SKA32869.1	SAMN02745673_00728	SAMN02745673_04093	Malate synthase; Belongs to the malate synthase family.	Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.449
SJZ55477.1	fumC	SAMN02745673_00728	SAMN02745673_04141	Malate synthase; Belongs to the malate synthase family.	Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.927
SJZ59771.1	SJZ59792.1	SAMN02745673_00870	SAMN02745673_00871	Hypothetical protein.	Uncharacterized protein, MTH1187 family.	0.648
SJZ59771.1	SJZ59825.1	SAMN02745673_00870	SAMN02745673_00872	Hypothetical protein.	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	0.649
SJZ59792.1	SJZ59771.1	SAMN02745673_00871	SAMN02745673_00870	Uncharacterized protein, MTH1187 family.	Hypothetical protein.	0.648
SJZ59792.1	SJZ59825.1	SAMN02745673_00871	SAMN02745673_00872	Uncharacterized protein, MTH1187 family.	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	0.701
SJZ59825.1	SJZ55477.1	SAMN02745673_00872	SAMN02745673_00728	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Malate synthase; Belongs to the malate synthase family.	0.773
SJZ59825.1	SJZ59771.1	SAMN02745673_00872	SAMN02745673_00870	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Hypothetical protein.	0.649
SJZ59825.1	SJZ59792.1	SAMN02745673_00872	SAMN02745673_00871	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Uncharacterized protein, MTH1187 family.	0.701
SJZ59825.1	SKA02021.1	SAMN02745673_00872	SAMN02745673_02183	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Maleylpyruvate isomerase.	0.828
SJZ59825.1	SKA19973.1	SAMN02745673_00872	SAMN02745673_03024	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Imidazolonepropionase.	0.726
SJZ59825.1	SKA32869.1	SAMN02745673_00872	SAMN02745673_04093	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.622
SJZ59825.1	SKA32875.1	SAMN02745673_00872	SAMN02745673_04094	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Succinate dehydrogenase subunit A.	0.632
SJZ59825.1	SKA32877.1	SAMN02745673_00872	SAMN02745673_04095	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Succinate dehydrogenase subunit C.	0.757
SJZ59825.1	SKA32909.1	SAMN02745673_00872	SAMN02745673_04101	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Succinate dehydrogenase subunit A.	0.632
SJZ59825.1	fumC	SAMN02745673_00872	SAMN02745673_04141	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.773
SKA02021.1	SJZ59825.1	SAMN02745673_02183	SAMN02745673_00872	Maleylpyruvate isomerase.	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	0.828
SKA19973.1	SJZ59825.1	SAMN02745673_03024	SAMN02745673_00872	Imidazolonepropionase.	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).	0.726
SKA32869.1	SJZ55477.1	SAMN02745673_04093	SAMN02745673_00728	Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	Malate synthase; Belongs to the malate synthase family.	0.449

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 116

1.35

2.24

2.26e-10

GO:0010467

Gene expression

11 of 203

1.15

1.66

2.26e-10

GO:0009059

Macromolecule biosynthetic process

11 of 227

1.1

1.54

2.26e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 354

0.91

1.05

1.55e-08

GO:0044238

Primary metabolic process

11 of 1054

0.44

0.36

0.0010

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 57

1.66

3.72

1.68e-13

GO:0019843

rRNA binding

5 of 41

1.5

1.61

8.00e-05

GO:0003723

RNA binding

6 of 91

1.24

1.28

8.44e-05

GO:0003676

Nucleic acid binding

7 of 415

0.64

0.39

0.0358

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 60

1.64

3.71

5.03e-14

GO:0015935

Small ribosomal subunit

2 of 6

1.94

1.09

0.0077

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1083

Mixed, incl. Small ribosomal subunit, and Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like

6 of 10

2.19

4.53

1.70e-10

CL:1043

Structural constituent of ribosome

11 of 56

1.71

4.35

3.06e-16

CL:1044

Structural constituent of ribosome

8 of 44

1.68

3.38

3.99e-11

CL:1045

Structural constituent of ribosome

7 of 37

1.69

3.12

1.30e-09

CL:1132

rRNA-binding

3 of 11

1.85

1.62

0.00045

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 60

1.64

3.71

4.67e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 48

1.69

3.62

3.59e-12

GOCC:0015935

Small ribosomal subunit

4 of 12

1.94

2.36

9.51e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 10

1.89

1.68

0.00036

GOCC:0043229

Intracellular organelle

10 of 311

0.92

1.04

1.79e-07

GOCC:0005622

Intracellular

11 of 1193

0.38

0.32

0.0018

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 58

1.65

3.76

6.24e-14

KW-0699

rRNA-binding

5 of 38

1.54

1.82

1.79e-05

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