STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vgbVirginiamycin B lyase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. (298 aa)    
Predicted Functional Partners:
SJZ94191.1
DNA-binding transcriptional regulator, ArsR family.
  
     0.623
SJZ89904.1
Streptomycin 3-kinase; Belongs to the aminoglycoside phosphotransferase family.
  
     0.571
SJZ93600.1
Pimeloyl-ACP methyl ester carboxylesterase.
       0.563
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.561
SJZ93806.1
Kanamycin kinase; Belongs to the aminoglycoside phosphotransferase family.
  
     0.494
SJZ87465.1
23S rRNA (adenine-N6)-dimethyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
  
   
 0.492
SJZ42995.1
Hypothetical protein.
  
     0.467
SKA33397.1
Hypothetical protein.
  
     0.467
SKA23238.1
Methylase involved in ubiquinone/menaquinone biosynthesis.
  
     0.456
SJZ62208.1
Dihydrofolate reductase.
  
     0.440
Your Current Organism:
Marinactinospora thermotolerans
NCBI taxonomy Id: 1122192
Other names: M. thermotolerans DSM 45154, Marinactinospora thermotolerans DSM 45154
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