STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA36032.1Proteasome assembly chaperone (PAC2) family protein. (282 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.712
SKA22724.1
Cytochrome c oxidase assembly protein subunit 15.
  
     0.633
SKA36024.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.574
SKA39146.1
IMP dehydrogenase.
  
     0.538
SJZ61640.1
Predicted ATP-dependent carboligase, ATP-grasp superfamily.
 
 
  
0.522
SKA22270.1
Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.512
prcB
Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 
   0.468
nucS
Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.465
prcA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
  
 
   0.451
SJZ39497.1
Predicted transcriptional regulators.
  
     0.432
Your Current Organism:
Marinactinospora thermotolerans
NCBI taxonomy Id: 1122192
Other names: M. thermotolerans DSM 45154, Marinactinospora thermotolerans DSM 45154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.