node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEB09813.1 | folE | SAMN02745729_11727 | SAMN02745729_10287 | 6-pyruvoyl tetrahydropterin synthase. | GTP cyclohydrolase I. | 0.881 |
SEB09813.1 | guaA | SAMN02745729_11727 | SAMN02745729_105124 | 6-pyruvoyl tetrahydropterin synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.493 |
SEB09813.1 | queC | SAMN02745729_11727 | SAMN02745729_103250 | 6-pyruvoyl tetrahydropterin synthase. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.901 |
SEB09813.1 | queE | SAMN02745729_11727 | SAMN02745729_102131 | 6-pyruvoyl tetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.942 |
SEB09813.1 | queF | SAMN02745729_11727 | SAMN02745729_10418 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.881 |
SEB12208.1 | queE | SAMN02745729_11953 | SAMN02745729_102131 | Undecaprenyl-diphosphatase. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.482 |
apt | guaA | SAMN02745729_102129 | SAMN02745729_105124 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.990 |
apt | purF | SAMN02745729_102129 | SAMN02745729_10262 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.539 |
apt | queE | SAMN02745729_102129 | SAMN02745729_102131 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.641 |
apt | rdgC | SAMN02745729_102129 | SAMN02745729_102130 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Recombination associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | 0.574 |
folE | SEB09813.1 | SAMN02745729_10287 | SAMN02745729_11727 | GTP cyclohydrolase I. | 6-pyruvoyl tetrahydropterin synthase. | 0.881 |
folE | queE | SAMN02745729_10287 | SAMN02745729_102131 | GTP cyclohydrolase I. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.590 |
folE | queF | SAMN02745729_10287 | SAMN02745729_10418 | GTP cyclohydrolase I. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.542 |
glmS | guaA | SAMN02745729_12125 | SAMN02745729_105124 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.643 |
glmS | purF | SAMN02745729_12125 | SAMN02745729_10262 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.896 |
glmS | queC | SAMN02745729_12125 | SAMN02745729_103250 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.459 |
glmS | queE | SAMN02745729_12125 | SAMN02745729_102131 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.528 |
guaA | SEB09813.1 | SAMN02745729_105124 | SAMN02745729_11727 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydropterin synthase. | 0.493 |
guaA | apt | SAMN02745729_105124 | SAMN02745729_102129 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.990 |
guaA | glmS | SAMN02745729_105124 | SAMN02745729_12125 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.643 |