STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mntRIron (metal) dependent repressor, DtxR family; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family. (138 aa)    
Predicted Functional Partners:
SDW24702.1
Zinc transport system ATP-binding protein.
  
 
 0.791
metN
D-methionine transport system ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
    
   0.664
SDW11408.1
Zinc transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
 
 0.649
SDW22382.1
Zinc transport system substrate-binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
 
 0.649
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.637
SDW24643.1
Zinc transport system permease protein.
  
 
 0.636
SDW24675.1
Zinc transport system permease protein.
  
 
 0.636
SDW23103.1
D-alanine transaminase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
       0.484
SDW89581.1
Fur family transcriptional regulator, peroxide stress response regulator; Belongs to the Fur family.
  
  
 0.456
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.425
Your Current Organism:
Marinococcus luteus
NCBI taxonomy Id: 1122204
Other names: CCTCC AA 208014, DSM 23126, KCTC 13214, M. luteus, Marinococcus luteus Wang et al. 2009, YIM 91094
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