SDW23498.1 protein (Marinococcus luteus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

SDW23498.1

3D (Asp-Asp-Asp) domain-containing protein. (235 aa)

Predicted Functional Partners:

SDW21444.1

0.891

SDW41893.1

0.752

SDW09944.1

0.725

cinA

0.723

SDW84622.1

0.687

guaA

0.681

SDW74545.1

0.680

SDW18346.1

0.623

SDW25195.1

0.618

SDW23759.1

0.577

Your Current Organism:

Marinococcus luteus

NCBI taxonomy Id: 1122204
Other names: CCTCC AA 208014, DSM 23126, KCTC 13214, M. luteus, Marinococcus luteus Wang et al. 2009, YIM 91094

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDW09944.1	SDW23498.1	SAMN05421781_0442	SAMN05421781_0932	3D (Asp-Asp-Asp) domain-containing protein.	3D (Asp-Asp-Asp) domain-containing protein.	0.725
SDW18346.1	SDW23498.1	SAMN05421781_0752	SAMN05421781_0932	Pyrimidine-nucleoside phosphorylase.	3D (Asp-Asp-Asp) domain-containing protein.	0.623
SDW18346.1	SDW25195.1	SAMN05421781_0752	SAMN05421781_0989	Pyrimidine-nucleoside phosphorylase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.990
SDW18346.1	SDW84622.1	SAMN05421781_0752	SAMN05421781_2516	Pyrimidine-nucleoside phosphorylase.	Polysaccharide deacetylase family sporulation protein PdaB.	0.523
SDW18346.1	guaA	SAMN05421781_0752	SAMN05421781_2552	Pyrimidine-nucleoside phosphorylase.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.471
SDW21444.1	SDW23498.1	SAMN05421781_0863	SAMN05421781_0932	3D (Asp-Asp-Asp) domain-containing protein.	3D (Asp-Asp-Asp) domain-containing protein.	0.891
SDW21444.1	SDW25195.1	SAMN05421781_0863	SAMN05421781_0989	3D (Asp-Asp-Asp) domain-containing protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.487
SDW21444.1	SDW74545.1	SAMN05421781_0863	SAMN05421781_2223	3D (Asp-Asp-Asp) domain-containing protein.	Tetrapyrrole methylase family protein / MazG family protein.	0.563
SDW21444.1	SDW84622.1	SAMN05421781_0863	SAMN05421781_2516	3D (Asp-Asp-Asp) domain-containing protein.	Polysaccharide deacetylase family sporulation protein PdaB.	0.745
SDW21444.1	cinA	SAMN05421781_0863	SAMN05421781_0282	3D (Asp-Asp-Asp) domain-containing protein.	Competence/damage-inducible protein cinA; Belongs to the CinA family.	0.705
SDW21444.1	guaA	SAMN05421781_0863	SAMN05421781_2552	3D (Asp-Asp-Asp) domain-containing protein.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.708
SDW23498.1	SDW09944.1	SAMN05421781_0932	SAMN05421781_0442	3D (Asp-Asp-Asp) domain-containing protein.	3D (Asp-Asp-Asp) domain-containing protein.	0.725
SDW23498.1	SDW18346.1	SAMN05421781_0932	SAMN05421781_0752	3D (Asp-Asp-Asp) domain-containing protein.	Pyrimidine-nucleoside phosphorylase.	0.623
SDW23498.1	SDW21444.1	SAMN05421781_0932	SAMN05421781_0863	3D (Asp-Asp-Asp) domain-containing protein.	3D (Asp-Asp-Asp) domain-containing protein.	0.891
SDW23498.1	SDW23759.1	SAMN05421781_0932	SAMN05421781_0940	3D (Asp-Asp-Asp) domain-containing protein.	Competence-related pilin export protein ComGA.	0.577
SDW23498.1	SDW25195.1	SAMN05421781_0932	SAMN05421781_0989	3D (Asp-Asp-Asp) domain-containing protein.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.618
SDW23498.1	SDW41893.1	SAMN05421781_0932	SAMN05421781_1350	3D (Asp-Asp-Asp) domain-containing protein.	3D (Asp-Asp-Asp) domain-containing protein.	0.752
SDW23498.1	SDW74545.1	SAMN05421781_0932	SAMN05421781_2223	3D (Asp-Asp-Asp) domain-containing protein.	Tetrapyrrole methylase family protein / MazG family protein.	0.680
SDW23498.1	SDW84622.1	SAMN05421781_0932	SAMN05421781_2516	3D (Asp-Asp-Asp) domain-containing protein.	Polysaccharide deacetylase family sporulation protein PdaB.	0.687
SDW23498.1	cinA	SAMN05421781_0932	SAMN05421781_0282	3D (Asp-Asp-Asp) domain-containing protein.	Competence/damage-inducible protein cinA; Belongs to the CinA family.	0.723

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Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.851

expected number of edges:

13

PPI enrichment p-value:

0.0073

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008216

Spermidine metabolic process

3 of 8

2.02

1.21

0.0047

GO:0008295

Spermidine biosynthetic process

2 of 4

2.15

0.79

0.0346

GO:1901564

Organonitrogen compound metabolic process

10 of 702

0.6

0.45

0.0047

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016407

Acetyltransferase activity

4 of 28

1.6

1.23

0.0021

GO:0008080

N-acetyltransferase activity

3 of 24

1.55

0.85

0.0169

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4479

Mixed, incl. Spermidine metabolic process, and Methionine biosynthesis

7 of 26

1.88

3.55

1.75e-09

CL:4482

Polyamine biosynthesis, and Spermine metabolic process

4 of 7

2.21

2.62

6.55e-06

CL:4511

Mixed, incl. Acetyltransferase (GNAT) domain, and Spermine metabolic process

3 of 10

1.93

1.45

0.0013

CL:4513

Acetyltransferase (GNAT) domain, and DeoR C terminal sensor domain

2 of 5

2.05

0.83

0.0280

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00330

Arginine and proline metabolism

3 of 30

1.45

0.78

0.0214

map00360

Phenylalanine metabolism

2 of 13

1.64

0.67

0.0489

map01100

Metabolic pathways

10 of 1082

0.42

0.3

0.0214

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0745

Spermidine biosynthesis

2 of 4

2.15

0.76

0.0395

KW-0620

Polyamine biosynthesis

2 of 4

2.15

0.76

0.0395

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13420

Acetyltransferase (GNAT) domain

3 of 5

2.23

1.6

0.00094

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