STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmdA2,3-dimethylmalate dehydratase large subunit. (422 aa)    
Predicted Functional Partners:
DmdB_1
2,3-dimethylmalate dehydratase small subunit.
 0.999
DmdB_2
2,3-dimethylmalate dehydratase small subunit.
 0.999
hicd
Homoisocitrate dehydrogenase.
 0.984
pyk
Pyruvate kinase.
    
 0.972
dmlA
D-malate dehydrogenase [decarboxylating].
 0.949
leuA_3
2-isopropylmalate synthase.
 
 
 0.945
leuA_1
2-isopropylmalate synthase.
 
 
 0.938
GCA_000711905_00322
Citrate (Re)-synthase.
 
 
 0.888
ilvC
Ketol-acid reductoisomerase (NAD(+)).
 
  
 0.888
leuA_2
2-isopropylmalate synthase.
 
 
 0.882
Your Current Organism:
Methermicoccus shengliensis
NCBI taxonomy Id: 1122233
Other names: M. shengliensis DSM 18856, Methermicoccus shengliensis DSM 18856
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.