DAI18_09430 protein (Microvirgula aerodenitrificans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

DAI18_09430

Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (201 aa)

Predicted Functional Partners:

DAI18_09435

0.959

DAI18_09405

0.957

DAI18_09400

0.955

DAI18_09415

0.954

DAI18_09450

0.953

DAI18_09425

0.953

DAI18_09395

0.953

DAI18_09440

0.952

DAI18_09410

0.952

DAI18_09445

0.949

Your Current Organism:

Microvirgula aerodenitrificans

NCBI taxonomy Id: 1122240
Other names: M. aerodenitrificans DSM 15089, Microvirgula aerodenitrificans DSM 15089

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAI18_09395	DAI18_09400	GCA_000620105_02518	GCA_000620105_02517	Unannotated protein.	Unannotated protein.	0.955
DAI18_09395	DAI18_09405	GCA_000620105_02518	GCA_000620105_02516	Unannotated protein.	Unannotated protein.	0.997
DAI18_09395	DAI18_09410	GCA_000620105_02518	GCA_000620105_02515	Unannotated protein.	Unannotated protein.	0.954
DAI18_09395	DAI18_09415	GCA_000620105_02518	GCA_000620105_02514	Unannotated protein.	Unannotated protein.	0.953
DAI18_09395	DAI18_09425	GCA_000620105_02518	GCA_000620105_02512	Unannotated protein.	Unannotated protein.	0.980
DAI18_09395	DAI18_09430	GCA_000620105_02518	GCA_000620105_02511	Unannotated protein.	Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.953
DAI18_09395	DAI18_09435	GCA_000620105_02518	GCA_000620105_02510	Unannotated protein.	Unannotated protein.	0.954
DAI18_09395	DAI18_09440	GCA_000620105_02518	GCA_000620105_02509	Unannotated protein.	Unannotated protein.	0.945
DAI18_09395	DAI18_09445	GCA_000620105_02518	GCA_000620105_02508	Unannotated protein.	Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.993
DAI18_09395	DAI18_09450	GCA_000620105_02518	GCA_000620105_02507	Unannotated protein.	Unannotated protein.	0.953
DAI18_09400	DAI18_09395	GCA_000620105_02517	GCA_000620105_02518	Unannotated protein.	Unannotated protein.	0.955
DAI18_09400	DAI18_09405	GCA_000620105_02517	GCA_000620105_02516	Unannotated protein.	Unannotated protein.	0.991
DAI18_09400	DAI18_09410	GCA_000620105_02517	GCA_000620105_02515	Unannotated protein.	Unannotated protein.	0.952
DAI18_09400	DAI18_09415	GCA_000620105_02517	GCA_000620105_02514	Unannotated protein.	Unannotated protein.	0.953
DAI18_09400	DAI18_09425	GCA_000620105_02517	GCA_000620105_02512	Unannotated protein.	Unannotated protein.	0.952
DAI18_09400	DAI18_09430	GCA_000620105_02517	GCA_000620105_02511	Unannotated protein.	Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.955
DAI18_09400	DAI18_09435	GCA_000620105_02517	GCA_000620105_02510	Unannotated protein.	Unannotated protein.	0.953
DAI18_09400	DAI18_09440	GCA_000620105_02517	GCA_000620105_02509	Unannotated protein.	Unannotated protein.	0.951
DAI18_09400	DAI18_09445	GCA_000620105_02517	GCA_000620105_02508	Unannotated protein.	Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.950
DAI18_09400	DAI18_09450	GCA_000620105_02517	GCA_000620105_02507	Unannotated protein.	Unannotated protein.	0.959

page 1 of 6

Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

3

PPI enrichment p-value:

0.575

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042545

Cell wall modification

2 of 2

2.54

0.78

0.0383

GO:0005975

Carbohydrate metabolic process

6 of 259

0.91

0.5

0.0383

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045330

Aspartyl esterase activity

2 of 2

2.54

1.12

0.0092

GO:0030599

Pectinesterase activity

2 of 2

2.54

1.12

0.0092

GO:0016788

Hydrolase activity, acting on ester bonds

5 of 139

1.1

0.76

0.0081

GO:0016787

Hydrolase activity

9 of 622

0.71

0.55

0.0020

GO:0003824

Catalytic activity

11 of 1823

0.33

0.25

0.0336

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4894

Mixed, incl. Pectin lyase fold/virulence factor, and SGNH hydrolase-type esterase domain

11 of 34

2.05

6.83

1.23e-19

CL:4897

Mixed, incl. Pectin lyase fold, and Rhamnogalacturonan acetylesterase RhgT-like

7 of 15

2.21

5.15

4.70e-12

CL:4899

Pectin lyase fold, and Rhamnogalacturonan acetylesterase RhgT-like

6 of 10

2.32

4.81

1.14e-10

CL:4942

Mixed, incl. Six-hairpin glycosidase-like superfamily, and Class II aldolase/adducin N-terminal

4 of 10

2.15

2.66

4.33e-06

CL:4909

Pectin lyase fold, and Alpha/beta hydrolase fold

3 of 5

2.32

2.1

0.00010

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00040

Pentose and glucuronate interconversions

4 of 28

1.7

1.71

0.00015

map01040

Biosynthesis of unsaturated fatty acids

2 of 13

1.73

0.69

0.0450

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005576

Extracellular region

5 of 183

0.98

0.57

0.0281

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0326

Glycosidase

3 of 31

1.53

0.82

0.0195

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037459

Rhamnogalacturonan acetylesterase RhgT-like

3 of 3

2.54

1.8

0.00048

IPR013830

SGNH hydrolase-type esterase domain

3 of 5

2.32

1.69

0.00066

IPR012334

Pectin lyase fold

3 of 6

2.24

1.68

0.00066

IPR036514

SGNH hydrolase superfamily

3 of 8

2.12

1.56

0.00097

IPR011050

Pectin lyase fold/virulence factor

3 of 9

2.07

1.54

0.0010

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00710

Parallel beta-helix repeats

2 of 5

2.15

0.94

0.0175

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