STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXSHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (393 aa)    
Predicted Functional Partners:
SFC26520.1
Methionine biosynthesis protein MetW.
  
 0.997
SFC33514.1
O-acetylhomoserine (thiol)-lyase.
 
 0.989
SFC21766.1
Homoserine dehydrogenase.
 
 
 0.967
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.963
SFB89216.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.929
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.929
SFC00854.1
Phosphoserine phosphatase.
     
 0.925
SFC46037.1
Phosphoserine phosphatase.
   
 
 0.916
SFB99378.1
Aspartate kinase; Belongs to the aspartokinase family.
   
 0.858
SFB88721.1
Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
  
 
0.821
Your Current Organism:
Marinospirillum celere
NCBI taxonomy Id: 1122252
Other names: DSM 18438, LMG 24610, LMG:24610, M. celere, Marinospirillum celere Namsaraev et al. 2009, VKM 2416, strain v1c_Sn-red
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