node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFB89216.1 | SFC37836.1 | SAMN05660443_0770 | SAMN05660443_2421 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADPH) large subunit. | 0.417 |
SFB89216.1 | SFC37946.1 | SAMN05660443_0770 | SAMN05660443_2427 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADH) large subunit. | 0.417 |
SFB89216.1 | SFC50804.1 | SAMN05660443_0770 | SAMN05660443_2894 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine oxidase. | 0.819 |
SFB89216.1 | glyA | SAMN05660443_0770 | SAMN05660443_1839 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
SFB89568.1 | SFC50804.1 | SAMN05660443_0789 | SAMN05660443_2894 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glycine oxidase. | 0.835 |
SFB98491.1 | SFC19839.1 | SAMN05660443_0999 | SAMN05660443_1849 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | Sulfide:quinone oxidoreductase. | 0.746 |
SFB98491.1 | SFC37836.1 | SAMN05660443_0999 | SAMN05660443_2421 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | Glutamate synthase (NADPH) large subunit. | 0.943 |
SFB98491.1 | SFC37946.1 | SAMN05660443_0999 | SAMN05660443_2427 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | Glutamate synthase (NADH) large subunit. | 0.943 |
SFB98491.1 | SFC50804.1 | SAMN05660443_0999 | SAMN05660443_2894 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | Glycine oxidase. | 0.896 |
SFB98491.1 | bioF | SAMN05660443_0999 | SAMN05660443_0197 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.475 |
SFB98491.1 | glyA | SAMN05660443_0999 | SAMN05660443_1839 | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.538 |
SFC19839.1 | SFB98491.1 | SAMN05660443_1849 | SAMN05660443_0999 | Sulfide:quinone oxidoreductase. | Sulfide dehydrogenase (flavocytochrome c), flavoprotein subunit. | 0.746 |
SFC19839.1 | SFC37836.1 | SAMN05660443_1849 | SAMN05660443_2421 | Sulfide:quinone oxidoreductase. | Glutamate synthase (NADPH) large subunit. | 0.943 |
SFC19839.1 | SFC37946.1 | SAMN05660443_1849 | SAMN05660443_2427 | Sulfide:quinone oxidoreductase. | Glutamate synthase (NADH) large subunit. | 0.943 |
SFC19839.1 | SFC50804.1 | SAMN05660443_1849 | SAMN05660443_2894 | Sulfide:quinone oxidoreductase. | Glycine oxidase. | 0.896 |
SFC19839.1 | bioF | SAMN05660443_1849 | SAMN05660443_0197 | Sulfide:quinone oxidoreductase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.475 |
SFC19839.1 | glyA | SAMN05660443_1849 | SAMN05660443_1839 | Sulfide:quinone oxidoreductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.538 |
SFC33001.1 | SFC50804.1 | SAMN05660443_2299 | SAMN05660443_2894 | Sulfur carrier protein. | Glycine oxidase. | 0.796 |
SFC33001.1 | thiG | SAMN05660443_2299 | SAMN05660443_2298 | Sulfur carrier protein. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
SFC37836.1 | SFB89216.1 | SAMN05660443_2421 | SAMN05660443_0770 | Glutamate synthase (NADPH) large subunit. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.417 |