STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (429 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.992
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.989
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.927
SIS31709.1
Amino acid adenylation domain-containing protein.
 
  
 0.864
SIS31406.1
Flagellum-specific peptidoglycan hydrolase FlgJ.
       0.711
SIS31408.1
1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family.
       0.696
cobA
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family.
 
   
 0.694
fabD
[acyl-carrier-protein] S-malonyltransferase.
    
 0.667
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.646
SIS34147.1
Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.593
Your Current Organism:
Chryseobacterium joostei
NCBI taxonomy Id: 112234
Other names: C. joostei, CCUG 46665, Chryseobacterium joostei Hugo et al. 2003 emend. Montero-Calasanz et al. 2014, DSM 16927, LMG 18212, LMG:18212, strain Ix 5a
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