STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaBCPhosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.942
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.927
SIS36381.1
Acyl carrier protein phosphodiesterase.
     
  0.900
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.880
SIS39359.1
Aspartate aminotransferase.
 
  0.855
SIS29428.1
Aspartate aminotransferase.
  
  0.836
SIS36035.1
Aspartate aminotransferase.
  
  0.836
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.808
SIS31488.1
Cystathionine gamma-lyase.
   
 
  0.804
SIS53393.1
DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA.
 
    0.784
Your Current Organism:
Chryseobacterium joostei
NCBI taxonomy Id: 112234
Other names: C. joostei, CCUG 46665, Chryseobacterium joostei Hugo et al. 2003 emend. Montero-Calasanz et al. 2014, DSM 16927, LMG 18212, LMG:18212, strain Ix 5a
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