STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF07347.1NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. (123 aa)    
Predicted Functional Partners:
SHE75956.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
  0.771
cinA
Competence/damage-inducible protein cinA; Belongs to the CinA family.
    
  0.766
SHE51564.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.744
SHF13372.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.738
SHF07329.1
DNA-binding transcriptional regulator, GntR family.
  
    0.701
SHE41213.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.622
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.445
SHF28993.1
8-oxo-dGTP diphosphatase; Belongs to the Nudix hydrolase family.
  
     0.425
SHE60245.1
Metal dependent phosphohydrolase.
  
     0.410
plsY
Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
  0.409
Your Current Organism:
Seinonella peptonophila
NCBI taxonomy Id: 112248
Other names: ATCC 27302, DSM 44666, JCM 10113, KCTC 9740, S. peptonophila, Thermoactinomyces peptonophilus
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