node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMC42104.1 | SMC42877.1 | SAMN02745168_0852 | SAMN02745168_0912 | Homoserine dehydrogenase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.438 |
SMC42104.1 | SMC64972.1 | SAMN02745168_0852 | SAMN02745168_1997 | Homoserine dehydrogenase. | Threonine dehydratase. | 0.915 |
SMC42104.1 | glyA | SAMN02745168_0852 | SAMN02745168_0488 | Homoserine dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.551 |
SMC42104.1 | trpA | SAMN02745168_0852 | SAMN02745168_2134 | Homoserine dehydrogenase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.557 |
SMC42104.1 | trpB | SAMN02745168_0852 | SAMN02745168_2135 | Homoserine dehydrogenase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.485 |
SMC42104.1 | trpF | SAMN02745168_0852 | SAMN02745168_0112 | Homoserine dehydrogenase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.479 |
SMC42877.1 | SMC42104.1 | SAMN02745168_0912 | SAMN02745168_0852 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Homoserine dehydrogenase. | 0.438 |
SMC42877.1 | SMC46328.1 | SAMN02745168_0912 | SAMN02745168_0969 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.426 |
SMC42877.1 | SMC64972.1 | SAMN02745168_0912 | SAMN02745168_1997 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Threonine dehydratase. | 0.806 |
SMC42877.1 | glyA | SAMN02745168_0912 | SAMN02745168_0488 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.791 |
SMC42877.1 | trpA | SAMN02745168_0912 | SAMN02745168_2134 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.997 |
SMC42877.1 | trpB | SAMN02745168_0912 | SAMN02745168_2135 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.828 |
SMC42877.1 | trpC | SAMN02745168_0912 | SAMN02745168_0113 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.940 |
SMC42877.1 | trpF | SAMN02745168_0912 | SAMN02745168_0112 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.600 |
SMC46328.1 | SMC42877.1 | SAMN02745168_0969 | SAMN02745168_0912 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.426 |
SMC46328.1 | SMC64972.1 | SAMN02745168_0969 | SAMN02745168_1997 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Threonine dehydratase. | 0.435 |
SMC46328.1 | glyA | SAMN02745168_0969 | SAMN02745168_0488 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.514 |
SMC46328.1 | trpA | SAMN02745168_0969 | SAMN02745168_2134 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.440 |
SMC46328.1 | trpB | SAMN02745168_0969 | SAMN02745168_2135 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.435 |
SMC64972.1 | SMC42104.1 | SAMN02745168_1997 | SAMN02745168_0852 | Threonine dehydratase. | Homoserine dehydrogenase. | 0.915 |