node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMC57290.1 | SMC84446.1 | SAMN02745168_1629 | SAMN02745168_0010 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit YajC. | 0.828 |
SMC57290.1 | SMC87646.1 | SAMN02745168_1629 | SAMN02745168_0183 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.973 |
SMC57290.1 | ffh | SAMN02745168_1629 | SAMN02745168_0948 | YidC/Oxa1 family membrane protein insertase. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.889 |
SMC57290.1 | ftsY | SAMN02745168_1629 | SAMN02745168_0996 | YidC/Oxa1 family membrane protein insertase. | Fused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.862 |
SMC57290.1 | pheT | SAMN02745168_1629 | SAMN02745168_0932 | YidC/Oxa1 family membrane protein insertase. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.574 |
SMC57290.1 | secA | SAMN02745168_1629 | SAMN02745168_0188 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.934 |
SMC57290.1 | secD | SAMN02745168_1629 | SAMN02745168_1271 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.985 |
SMC57290.1 | secE | SAMN02745168_1629 | SAMN02745168_0870 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.959 |
SMC57290.1 | secF | SAMN02745168_1629 | SAMN02745168_1272 | YidC/Oxa1 family membrane protein insertase. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.935 |
SMC57290.1 | secY | SAMN02745168_1629 | SAMN02745168_2340 | YidC/Oxa1 family membrane protein insertase. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.984 |
SMC84446.1 | SMC57290.1 | SAMN02745168_0010 | SAMN02745168_1629 | Preprotein translocase subunit YajC. | YidC/Oxa1 family membrane protein insertase. | 0.828 |
SMC84446.1 | SMC87646.1 | SAMN02745168_0010 | SAMN02745168_0183 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.870 |
SMC84446.1 | ffh | SAMN02745168_0010 | SAMN02745168_0948 | Preprotein translocase subunit YajC. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.853 |
SMC84446.1 | ftsY | SAMN02745168_0010 | SAMN02745168_0996 | Preprotein translocase subunit YajC. | Fused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.854 |
SMC84446.1 | secA | SAMN02745168_0010 | SAMN02745168_0188 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.890 |
SMC84446.1 | secD | SAMN02745168_0010 | SAMN02745168_1271 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.964 |
SMC84446.1 | secE | SAMN02745168_0010 | SAMN02745168_0870 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.925 |
SMC84446.1 | secF | SAMN02745168_0010 | SAMN02745168_1272 | Preprotein translocase subunit YajC. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.809 |
SMC84446.1 | secY | SAMN02745168_0010 | SAMN02745168_2340 | Preprotein translocase subunit YajC. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.904 |
SMC87646.1 | SMC57290.1 | SAMN02745168_0183 | SAMN02745168_1629 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | YidC/Oxa1 family membrane protein insertase. | 0.973 |