STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (450 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.995
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 0.993
pfp
6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.992
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.987
SMC90800.1
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.980
SMC54157.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.980
SMC50382.1
Fructose-bisphosphate aldolase, class II.
  
 
 0.970
SMC90076.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.945
SMC86498.1
Phosphoglucomutase.
 
 
 0.939
SMC90605.1
Mannose-1-phosphate guanylyltransferase / phosphomannomutase.
  
 0.929
Your Current Organism:
Papillibacter cinnamivorans
NCBI taxonomy Id: 1122930
Other names: P. cinnamivorans DSM 12816, Papillibacter cinnamivorans DSM 12816
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.