SHI86761.1 protein (Parasporobacterium paucivorans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

SHI86761.1

Hypothetical protein. (149 aa)

Predicted Functional Partners:

SHI86721.1

0.951

SHJ46265.1

0.714

SHI86837.1

0.692

SHI62632.1

0.572

SHJ19348.1

0.516

SHI79184.1

0.510

SHI86677.1

0.480

rlmH

0.427

SHJ34658.1

0.407

Your Current Organism:

Parasporobacterium paucivorans

NCBI taxonomy Id: 1122934
Other names: P. paucivorans DSM 15970, Parasporobacterium paucivorans DSM 15970

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHI62632.1	SHI86721.1	SAMN02745691_00551	SAMN02745691_00952	Hybrid cluster protein-associated redox disulfide domain-containing protein.	Hemerythrin-like domain-containing protein.	0.552
SHI62632.1	SHI86761.1	SAMN02745691_00551	SAMN02745691_00953	Hybrid cluster protein-associated redox disulfide domain-containing protein.	Hypothetical protein.	0.572
SHI79184.1	SHI86721.1	SAMN02745691_00825	SAMN02745691_00952	Sulfite exporter TauE/SafE.	Hemerythrin-like domain-containing protein.	0.457
SHI79184.1	SHI86761.1	SAMN02745691_00825	SAMN02745691_00953	Sulfite exporter TauE/SafE.	Hypothetical protein.	0.510
SHI79184.1	SHJ34658.1	SAMN02745691_00825	SAMN02745691_01799	Sulfite exporter TauE/SafE.	Iron only nitrogenase protein AnfO (AnfO_nitrog).	0.404
SHI86677.1	SHI86721.1	SAMN02745691_00951	SAMN02745691_00952	Chitobiase/beta-hexosaminidase C-terminal domain-containing protein.	Hemerythrin-like domain-containing protein.	0.480
SHI86677.1	SHI86761.1	SAMN02745691_00951	SAMN02745691_00953	Chitobiase/beta-hexosaminidase C-terminal domain-containing protein.	Hypothetical protein.	0.480
SHI86677.1	rlmH	SAMN02745691_00951	SAMN02745691_00950	Chitobiase/beta-hexosaminidase C-terminal domain-containing protein.	23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	0.675
SHI86721.1	SHI62632.1	SAMN02745691_00952	SAMN02745691_00551	Hemerythrin-like domain-containing protein.	Hybrid cluster protein-associated redox disulfide domain-containing protein.	0.552
SHI86721.1	SHI79184.1	SAMN02745691_00952	SAMN02745691_00825	Hemerythrin-like domain-containing protein.	Sulfite exporter TauE/SafE.	0.457
SHI86721.1	SHI86677.1	SAMN02745691_00952	SAMN02745691_00951	Hemerythrin-like domain-containing protein.	Chitobiase/beta-hexosaminidase C-terminal domain-containing protein.	0.480
SHI86721.1	SHI86761.1	SAMN02745691_00952	SAMN02745691_00953	Hemerythrin-like domain-containing protein.	Hypothetical protein.	0.951
SHI86721.1	SHI86837.1	SAMN02745691_00952	SAMN02745691_00954	Hemerythrin-like domain-containing protein.	Hybrid cluster protein-associated redox disulfide domain-containing protein.	0.711
SHI86721.1	SHJ19348.1	SAMN02745691_00952	SAMN02745691_01511	Hemerythrin-like domain-containing protein.	Lactoylglutathione lyase.	0.472
SHI86721.1	rlmH	SAMN02745691_00952	SAMN02745691_00950	Hemerythrin-like domain-containing protein.	23S rRNA (pseudouridine1915-N3)-methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	0.427
SHI86761.1	SHI62632.1	SAMN02745691_00953	SAMN02745691_00551	Hypothetical protein.	Hybrid cluster protein-associated redox disulfide domain-containing protein.	0.572
SHI86761.1	SHI79184.1	SAMN02745691_00953	SAMN02745691_00825	Hypothetical protein.	Sulfite exporter TauE/SafE.	0.510
SHI86761.1	SHI86677.1	SAMN02745691_00953	SAMN02745691_00951	Hypothetical protein.	Chitobiase/beta-hexosaminidase C-terminal domain-containing protein.	0.480
SHI86761.1	SHI86721.1	SAMN02745691_00953	SAMN02745691_00952	Hypothetical protein.	Hemerythrin-like domain-containing protein.	0.951
SHI86761.1	SHI86837.1	SAMN02745691_00953	SAMN02745691_00954	Hypothetical protein.	Hybrid cluster protein-associated redox disulfide domain-containing protein.	0.692

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Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.871

expected number of edges:

12

PPI enrichment p-value:

0.0535

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006298

Mismatch repair

3 of 6

2.23

1.7

0.00058

GO:0071897

DNA biosynthetic process

3 of 16

1.8

1.25

0.0030

GO:0006259

DNA metabolic process

6 of 131

1.19

1.09

0.00048

GO:0006281

DNA repair

4 of 58

1.37

1.04

0.0030

GO:0090304

Nucleic acid metabolic process

8 of 276

0.99

0.94

0.00015

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030983

Mismatched DNA binding

3 of 6

2.23

1.75

0.00045

GO:0140664

ATP-dependent DNA damage sensor activity

3 of 10

2.01

1.65

0.00055

GO:0004527

Exonuclease activity

3 of 13

1.89

1.55

0.00072

GO:0004518

Nuclease activity

4 of 42

1.51

1.37

0.00055

GO:0140097

Catalytic activity, acting on DNA

5 of 73

1.37

1.27

0.00045

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042575

DNA polymerase complex

2 of 4

2.23

1.02

0.0126

GO:0005634

Nucleus

2 of 25

1.43

0.64

0.0474

GO:0005622

Intracellular anatomical structure

9 of 1150

0.42

0.29

0.0400

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:582

Mixed, incl. DNA damage sensor activity, and Chromatin remodeling

6 of 18

2.05

3.58

1.34e-08

CL:584

Mixed, incl. Mismatch repair, and DNA polymerase complex

5 of 11

2.19

3.51

5.45e-08

CL:587

DNA polymerase complex, and Mismatch repair

4 of 5

2.43

3.23

6.03e-07

CL:580

Mismatch repair, and DNA repair

7 of 46

1.71

2.93

1.34e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03430

Mismatch repair

5 of 31

1.74

2.3

3.40e-06

map03030

DNA replication

4 of 31

1.64

1.68

0.00013

map03440

Homologous recombination

3 of 35

1.46

0.99

0.0062

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042575

DNA polymerase complex

2 of 4

2.23

0.92

0.0199

GOCC:0032300

Mismatch repair complex

2 of 4

2.23

0.92

0.0199

GOCC:0032991

Protein-containing complex

6 of 379

0.73

0.45

0.0238

GOCC:0005622

Intracellular

10 of 1162

0.46

0.33

0.0199

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0540

Nuclease

4 of 29

1.67

1.58

0.00029

KW-0269

Exonuclease

2 of 6

2.05

0.9

0.0201

KW-0239

DNA-directed DNA polymerase

2 of 7

1.99

0.9

0.0201

KW-0235

DNA replication

2 of 15

1.65

0.67

0.0481

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00534

ATPase domain of DNA mismatch repair MUTS family

2 of 4

2.23

1.03

0.0120

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