node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EPX83826.1 | EPX85943.1 | ruthe_02624 | ruthe_01664 | L-serine dehydratase, iron-sulfur-dependent, single chain form. | Acetolactate synthase, small subunit. | 0.518 |
EPX83826.1 | EPX87467.1 | ruthe_02624 | ruthe_00537 | L-serine dehydratase, iron-sulfur-dependent, single chain form. | Threonine dehydratase. | 0.897 |
EPX83826.1 | EPX87895.1 | ruthe_02624 | ruthe_00100 | L-serine dehydratase, iron-sulfur-dependent, single chain form. | Aminotransferase class-V. | 0.856 |
EPX83826.1 | glyA | ruthe_02624 | ruthe_02896 | L-serine dehydratase, iron-sulfur-dependent, single chain form. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.972 |
EPX83826.1 | metZ | ruthe_02624 | ruthe_00041 | L-serine dehydratase, iron-sulfur-dependent, single chain form. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.820 |
EPX84136.1 | EPX85943.1 | ruthe_02346 | ruthe_01664 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | Acetolactate synthase, small subunit. | 0.661 |
EPX84136.1 | EPX87388.1 | ruthe_02346 | ruthe_00458 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | L-threonine synthase. | 0.495 |
EPX84136.1 | EPX87467.1 | ruthe_02346 | ruthe_00537 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | Threonine dehydratase. | 0.913 |
EPX84136.1 | ilvE | ruthe_02346 | ruthe_02721 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.873 |
EPX84136.1 | metZ | ruthe_02346 | ruthe_00041 | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.862 |
EPX85943.1 | EPX83826.1 | ruthe_01664 | ruthe_02624 | Acetolactate synthase, small subunit. | L-serine dehydratase, iron-sulfur-dependent, single chain form. | 0.518 |
EPX85943.1 | EPX84136.1 | ruthe_01664 | ruthe_02346 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. | 0.661 |
EPX85943.1 | EPX87388.1 | ruthe_01664 | ruthe_00458 | Acetolactate synthase, small subunit. | L-threonine synthase. | 0.808 |
EPX85943.1 | EPX87467.1 | ruthe_01664 | ruthe_00537 | Acetolactate synthase, small subunit. | Threonine dehydratase. | 0.986 |
EPX85943.1 | ilvE | ruthe_01664 | ruthe_02721 | Acetolactate synthase, small subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.732 |
EPX85943.1 | metZ | ruthe_01664 | ruthe_00041 | Acetolactate synthase, small subunit. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.545 |
EPX86466.1 | EPX87467.1 | ruthe_01281 | ruthe_00537 | Methionine synthase I (cobalamin-dependent), methyltransferase domain protein. | Threonine dehydratase. | 0.891 |
EPX86466.1 | EPX87895.1 | ruthe_01281 | ruthe_00100 | Methionine synthase I (cobalamin-dependent), methyltransferase domain protein. | Aminotransferase class-V. | 0.425 |
EPX86466.1 | glyA | ruthe_01281 | ruthe_02896 | Methionine synthase I (cobalamin-dependent), methyltransferase domain protein. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.893 |
EPX86466.1 | metZ | ruthe_01281 | ruthe_00041 | Methionine synthase I (cobalamin-dependent), methyltransferase domain protein. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.950 |