STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPX87467.1Threonine dehydratase. (324 aa)    
Predicted Functional Partners:
EPX85943.1
Acetolactate synthase, small subunit.
  
 
 0.986
EPX87388.1
L-threonine synthase.
  
 
 0.965
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.944
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.930
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
 0.917
EPX84136.1
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.913
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.913
EPX83826.1
L-serine dehydratase, iron-sulfur-dependent, single chain form.
  
 
 0.897
EPX86466.1
Methionine synthase I (cobalamin-dependent), methyltransferase domain protein.
  
 0.891
EPX87895.1
Aminotransferase class-V.
  
 0.890
Your Current Organism:
Rubellimicrobium thermophilum
NCBI taxonomy Id: 1123069
Other names: R. thermophilum DSM 16684, Rubellimicrobium thermophilum DSM 16684
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