STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPX86547.1Choline-sulfatase. (345 aa)    
Predicted Functional Partners:
EPX86546.1
Arylsulfatase A/related enzyme.
     0.990
betI
Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes.
 
   
 0.858
EPX86544.1
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
   
 0.715
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
    0.696
EPX86549.1
Choline ABC transporter, periplasmic binding protein.
 
     0.660
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
   
    0.659
EPX83115.1
Hypothetical protein.
   
    0.659
EPX86543.1
2,4-dihydroxyhept-2-enedioate aldolase; Belongs to the HpcH/HpaI aldolase family.
       0.625
EPX82374.1
Product; Related to short-chain alcohol dehydrogenase.
  
 
 0.588
EPX83153.1
Hypothetical protein.
  
 
 0.538
Your Current Organism:
Rubellimicrobium thermophilum
NCBI taxonomy Id: 1123069
Other names: R. thermophilum DSM 16684, Rubellimicrobium thermophilum DSM 16684
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.