STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPX84911.1Sugar kinase, ribokinase family. (349 aa)    
Predicted Functional Partners:
nth
DNA-(apurinic or apyrimidinic site) lyase/endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.849
EPX87356.1
5-deoxyglucuronate isomerase.
  
 
 0.799
EPX84909.1
O-6-methylguanine DNA methyltransferase.
     
 0.742
EPX86073.1
GMP synthase (glutamine-hydrolyzing); C-terminal domain or B subunit.
  
 
 0.727
EPX84912.1
Glutamine--fructose-6-phosphate transaminase.
  
 
 0.702
EPX86061.1
IMP dehydrogenase/GMP reductase.
   
 
 0.686
EPX84466.1
Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.656
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
    0.652
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.643
EPX84913.1
N-acetylglucosamine 6-phosphate deacetylase.
    
 0.641
Your Current Organism:
Rubellimicrobium thermophilum
NCBI taxonomy Id: 1123069
Other names: R. thermophilum DSM 16684, Rubellimicrobium thermophilum DSM 16684
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