STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (307 aa)    
Predicted Functional Partners:
EPX84376.1
CRISPR-associated protein, Cas2 family.
 
 
 0.999
EPX84369.1
CRISPR type I-E/ protein CasA/Cse1.
 
  
 0.968
EPX84371.1
CRISPR-associated protein, Cse4 family.
 
  
 0.968
EPX84372.1
CRISPR-associated protein, Cas5e family.
 
  
 0.961
EPX84374.1
CRISPR-associated protein, Cse3 family.
 
  
 0.956
EPX84368.1
CRISPR-associated helicase Cas3.
 
  
 0.913
EPX84469.1
CRISPR-associated endonuclease Cas3-HD.
 
  
 0.891
EPX84370.1
CRISPR type I-E/ protein CasB/Cse2.
  
  
 0.808
ihfB
Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
    
   0.790
EPX84373.1
Hypothetical protein.
       0.724
Your Current Organism:
Rubellimicrobium thermophilum
NCBI taxonomy Id: 1123069
Other names: R. thermophilum DSM 16684, Rubellimicrobium thermophilum DSM 16684
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.