node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHE31453.1 | SHF27525.1 | SAMN02745190_00132 | SAMN02745190_02264 | DNA polymerase-3 subunit delta'. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.725 |
SHE31453.1 | dnaX | SAMN02745190_00132 | SAMN02745190_00289 | DNA polymerase-3 subunit delta'. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.813 |
SHE31453.1 | topA | SAMN02745190_00132 | SAMN02745190_00429 | DNA polymerase-3 subunit delta'. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.592 |
SHE75588.1 | SHF27525.1 | SAMN02745190_01079 | SAMN02745190_02264 | Hypothetical protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.971 |
SHE75588.1 | topA | SAMN02745190_01079 | SAMN02745190_00429 | Hypothetical protein. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.603 |
SHE89174.1 | SHF27525.1 | SAMN02745190_01369 | SAMN02745190_02264 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.791 |
SHF27525.1 | SHE31453.1 | SAMN02745190_02264 | SAMN02745190_00132 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase-3 subunit delta'. | 0.725 |
SHF27525.1 | SHE75588.1 | SAMN02745190_02264 | SAMN02745190_01079 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein. | 0.971 |
SHF27525.1 | SHE89174.1 | SAMN02745190_02264 | SAMN02745190_01369 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.791 |
SHF27525.1 | SHF27549.1 | SAMN02745190_02264 | SAMN02745190_02265 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Protein of unknown function. | 0.752 |
SHF27525.1 | SHF27576.1 | SAMN02745190_02264 | SAMN02745190_02266 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Protein of unknown function. | 0.752 |
SHF27525.1 | dnaA | SAMN02745190_02264 | SAMN02745190_01709 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.946 |
SHF27525.1 | dnaG | SAMN02745190_02264 | SAMN02745190_00708 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.991 |
SHF27525.1 | dnaX | SAMN02745190_02264 | SAMN02745190_00289 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.725 |
SHF27525.1 | topA | SAMN02745190_02264 | SAMN02745190_00429 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.724 |
SHF27525.1 | tuf | SAMN02745190_02264 | SAMN02745190_01329 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.805 |
SHF27549.1 | SHF27525.1 | SAMN02745190_02265 | SAMN02745190_02264 | Protein of unknown function. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.752 |
SHF27549.1 | SHF27576.1 | SAMN02745190_02265 | SAMN02745190_02266 | Protein of unknown function. | Protein of unknown function. | 0.894 |
SHF27576.1 | SHF27525.1 | SAMN02745190_02266 | SAMN02745190_02264 | Protein of unknown function. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.752 |
SHF27576.1 | SHF27549.1 | SAMN02745190_02266 | SAMN02745190_02265 | Protein of unknown function. | Protein of unknown function. | 0.894 |