SIN64063.1 protein (Sphingorhabdus marina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

SIN64063.1

Cupin domain-containing protein. (166 aa)

Predicted Functional Partners:

SIN64054.1

0.803

SIN64068.1

0.776

SIN64041.1

0.773

SIN64048.1

0.773

SIN64074.1

0.757

SIN64079.1

0.757

SIN64087.1

0.757

SIN64094.1

0.757

SIN64101.1

0.757

SIN64109.1

0.757

Your Current Organism:

Sphingorhabdus marina

NCBI taxonomy Id: 1123272
Other names: S. marina DSM 22363, Sphingopyxis marina DSM 22363, Sphingopyxis marina FR1087, Sphingopyxis marina JCM 14161, Sphingopyxis sp. FR1087, Sphingorhabdus marina DSM 22363

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIN64041.1	SIN64048.1	SAMN02745824_1336	SAMN02745824_1337	Predicted arabinose efflux permease, MFS family.	Aldehyde dehydrogenase (acceptor).	0.773
SIN64041.1	SIN64054.1	SAMN02745824_1336	SAMN02745824_1338	Predicted arabinose efflux permease, MFS family.	Aminoacrylate hydrolase.	0.773
SIN64041.1	SIN64063.1	SAMN02745824_1336	SAMN02745824_1339	Predicted arabinose efflux permease, MFS family.	Cupin domain-containing protein.	0.773
SIN64041.1	SIN64068.1	SAMN02745824_1336	SAMN02745824_1340	Predicted arabinose efflux permease, MFS family.	Ornithine cyclodeaminase.	0.773
SIN64041.1	SIN64074.1	SAMN02745824_1336	SAMN02745824_1341	Predicted arabinose efflux permease, MFS family.	CubicO group peptidase, beta-lactamase class C family.	0.757
SIN64041.1	SIN64079.1	SAMN02745824_1336	SAMN02745824_1342	Predicted arabinose efflux permease, MFS family.	Glycoside/pentoside/hexuronide:cation symporter, GPH family.	0.757
SIN64041.1	SIN64087.1	SAMN02745824_1336	SAMN02745824_1343	Predicted arabinose efflux permease, MFS family.	Methyltransferase domain-containing protein.	0.759
SIN64041.1	SIN64094.1	SAMN02745824_1336	SAMN02745824_1344	Predicted arabinose efflux permease, MFS family.	Hypothetical protein.	0.757
SIN64041.1	SIN64101.1	SAMN02745824_1336	SAMN02745824_1345	Predicted arabinose efflux permease, MFS family.	Alpha/beta hydrolase family protein.	0.757
SIN64041.1	SIN64109.1	SAMN02745824_1336	SAMN02745824_1346	Predicted arabinose efflux permease, MFS family.	CubicO group peptidase, beta-lactamase class C family.	0.757
SIN64048.1	SIN64041.1	SAMN02745824_1337	SAMN02745824_1336	Aldehyde dehydrogenase (acceptor).	Predicted arabinose efflux permease, MFS family.	0.773
SIN64048.1	SIN64054.1	SAMN02745824_1337	SAMN02745824_1338	Aldehyde dehydrogenase (acceptor).	Aminoacrylate hydrolase.	0.785
SIN64048.1	SIN64063.1	SAMN02745824_1337	SAMN02745824_1339	Aldehyde dehydrogenase (acceptor).	Cupin domain-containing protein.	0.773
SIN64048.1	SIN64068.1	SAMN02745824_1337	SAMN02745824_1340	Aldehyde dehydrogenase (acceptor).	Ornithine cyclodeaminase.	0.807
SIN64048.1	SIN64074.1	SAMN02745824_1337	SAMN02745824_1341	Aldehyde dehydrogenase (acceptor).	CubicO group peptidase, beta-lactamase class C family.	0.757
SIN64048.1	SIN64079.1	SAMN02745824_1337	SAMN02745824_1342	Aldehyde dehydrogenase (acceptor).	Glycoside/pentoside/hexuronide:cation symporter, GPH family.	0.759
SIN64048.1	SIN64087.1	SAMN02745824_1337	SAMN02745824_1343	Aldehyde dehydrogenase (acceptor).	Methyltransferase domain-containing protein.	0.762
SIN64048.1	SIN64094.1	SAMN02745824_1337	SAMN02745824_1344	Aldehyde dehydrogenase (acceptor).	Hypothetical protein.	0.757
SIN64048.1	SIN64101.1	SAMN02745824_1337	SAMN02745824_1345	Aldehyde dehydrogenase (acceptor).	Alpha/beta hydrolase family protein.	0.757
SIN64048.1	SIN64109.1	SAMN02745824_1337	SAMN02745824_1346	Aldehyde dehydrogenase (acceptor).	CubicO group peptidase, beta-lactamase class C family.	0.757

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Network Stats

number of nodes:

5

number of edges:

7

average node degree:

2.8

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.255

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

6 of 16

2.18

3.97

4.08e-09

GO:0031564

Transcription antitermination

3 of 3

2.61

2.28

5.92e-05

GO:0006353

DNA-templated transcription, termination

3 of 4

2.48

2.24

6.48e-05

GO:0034654

Nucleobase-containing compound biosynthetic process

7 of 165

1.24

1.43

1.06e-05

GO:0010467

Gene expression

7 of 235

1.08

1.1

6.48e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 9

2.13

1.41

0.0020

GO:0003676

Nucleic acid binding

7 of 589

0.68

0.42

0.0294

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 10

2.09

1.7

0.00048

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1641

Transcription, DNA-templated, and SNF2, N-terminal

6 of 14

2.24

4.22

1.51e-09

CL:1659

DNA-templated transcription, termination

3 of 5

2.39

2.19

7.37e-05

CL:1645

RNA polymerase

3 of 5

2.39

2.19

7.37e-05

CL:1417

Translation, and Purine nucleoside triphosphate biosynthetic process

7 of 126

1.35

1.73

2.49e-06

CL:1369

Mixed, incl. NAD(P)+ transhydrogenase activity, and NAD synthase

2 of 7

2.07

0.92

0.0188

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

3 of 5

2.39

2.18

7.51e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 84

1.16

0.65

0.0270

MAP-5663205

Infectious disease

3 of 88

1.14

0.64

0.0270

MAP-1643685

Disease

3 of 93

1.12

0.63

0.0270

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008023

Transcription elongation factor complex

2 of 2

2.61

1.11

0.0097

GOCC:0000428

DNA-directed RNA polymerase complex

3 of 50

1.39

0.74

0.0237

GOCC:0005622

Intracellular

10 of 1477

0.44

0.32

0.0179

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0889

Transcription antitermination

3 of 3

2.61

2.35

4.47e-05

KW-0240

DNA-directed RNA polymerase

3 of 6

2.31

2.19

6.59e-05

KW-0804

Transcription

6 of 123

1.3

1.41

4.47e-05

KW-0806

Transcription termination

2 of 3

2.43

1.37

0.0029

KW-0548

Nucleotidyltransferase

3 of 46

1.42

0.93

0.0082

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