STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIO16637.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (876 aa)    
Predicted Functional Partners:
SIO16609.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 0.999
SIO16576.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.996
SIN65402.1
Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.963
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.958
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.955
SIN68077.1
O-acetylhomoserine sulfhydrylase.
  
 
 0.951
SIO10717.1
Aminomethyltransferase.
    
 0.939
SIN65829.1
Homoserine dehydrogenase.
  
 
 0.929
SIN63452.1
Cystathionine beta-lyase.
  
 
 0.925
SIN65271.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
   
 
 0.908
Your Current Organism:
Sphingorhabdus marina
NCBI taxonomy Id: 1123272
Other names: S. marina DSM 22363, Sphingopyxis marina DSM 22363, Sphingopyxis marina FR1087, Sphingopyxis marina JCM 14161, Sphingopyxis sp. FR1087, Sphingorhabdus marina DSM 22363
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