STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHH66084.1methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (167 aa)    
Predicted Functional Partners:
SHH66063.1
DNA-3-methyladenine glycosylase II.
 
 0.997
SHH49641.1
DNA-3-methyladenine glycosylase I.
    
 0.853
sigA
RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.710
SHI10257.1
Nucleotide-binding universal stress protein, UspA family.
  
    0.600
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.589
SHI20013.1
N-glycosylase/DNA lyase.
  
 
 0.544
SHH66034.1
DNA-binding transcriptional regulator, PadR family.
       0.448
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.438
SHH66009.1
Hypothetical protein.
       0.424
SHH58679.1
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase; Belongs to the sulfur carrier protein TusA family.
     
 0.420
Your Current Organism:
Sporobacter termitidis
NCBI taxonomy Id: 1123282
Other names: S. termitidis DSM 10068, Sporobacter termitidis DSM 10068
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.