node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHH62445.1 | glyA | SAMN02745823_00526 | SAMN02745823_01496 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.737 |
SHH62445.1 | trpA | SAMN02745823_00526 | SAMN02745823_03479 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.997 |
SHH62445.1 | trpB | SAMN02745823_00526 | SAMN02745823_03478 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.790 |
SHH62445.1 | trpC | SAMN02745823_00526 | SAMN02745823_03476 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.949 |
SHH62445.1 | trpF | SAMN02745823_00526 | SAMN02745823_03477 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.683 |
SHI02336.1 | SHI21441.1 | SAMN02745823_01969 | SAMN02745823_03473 | Amino acid adenylation domain-containing protein. | Anthranilate synthase component 1. | 0.967 |
SHI02336.1 | SHI21449.1 | SAMN02745823_01969 | SAMN02745823_03474 | Amino acid adenylation domain-containing protein. | Anthranilate synthase component 2. | 0.655 |
SHI02336.1 | glyA | SAMN02745823_01969 | SAMN02745823_01496 | Amino acid adenylation domain-containing protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.466 |
SHI02336.1 | trpA | SAMN02745823_01969 | SAMN02745823_03479 | Amino acid adenylation domain-containing protein. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.768 |
SHI02336.1 | trpB | SAMN02745823_01969 | SAMN02745823_03478 | Amino acid adenylation domain-containing protein. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.670 |
SHI02336.1 | trpD | SAMN02745823_01969 | SAMN02745823_03475 | Amino acid adenylation domain-containing protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.682 |
SHI21441.1 | SHI02336.1 | SAMN02745823_03473 | SAMN02745823_01969 | Anthranilate synthase component 1. | Amino acid adenylation domain-containing protein. | 0.967 |
SHI21441.1 | SHI21449.1 | SAMN02745823_03473 | SAMN02745823_03474 | Anthranilate synthase component 1. | Anthranilate synthase component 2. | 0.999 |
SHI21441.1 | SHI21493.1 | SAMN02745823_03473 | SAMN02745823_03480 | Anthranilate synthase component 1. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. | 0.512 |
SHI21441.1 | trpA | SAMN02745823_03473 | SAMN02745823_03479 | Anthranilate synthase component 1. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.973 |
SHI21441.1 | trpB | SAMN02745823_03473 | SAMN02745823_03478 | Anthranilate synthase component 1. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.972 |
SHI21441.1 | trpC | SAMN02745823_03473 | SAMN02745823_03476 | Anthranilate synthase component 1. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SHI21441.1 | trpD | SAMN02745823_03473 | SAMN02745823_03475 | Anthranilate synthase component 1. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SHI21441.1 | trpF | SAMN02745823_03473 | SAMN02745823_03477 | Anthranilate synthase component 1. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.985 |
SHI21449.1 | SHI02336.1 | SAMN02745823_03474 | SAMN02745823_01969 | Anthranilate synthase component 2. | Amino acid adenylation domain-containing protein. | 0.655 |