node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFL61822.1 | SFL61838.1 | SAMN04490355_101113 | SAMN04490355_101114 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.997 |
SFL61822.1 | SFL61908.1 | SAMN04490355_101113 | SAMN04490355_101118 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.747 |
SFL61822.1 | SFM02668.1 | SAMN04490355_101113 | SAMN04490355_10346 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Arabinose-5-phosphate isomerase. | 0.879 |
SFL61822.1 | kdsA | SAMN04490355_101113 | SAMN04490355_101115 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.984 |
SFL61822.1 | kdsB | SAMN04490355_101113 | SAMN04490355_101116 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.922 |
SFL61822.1 | lpxA | SAMN04490355_101113 | SAMN04490355_101122 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.493 |
SFL61822.1 | lpxB | SAMN04490355_101113 | SAMN04490355_101120 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.715 |
SFL61822.1 | lpxC | SAMN04490355_101113 | SAMN04490355_101124 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.660 |
SFL61822.1 | lpxD | SAMN04490355_101113 | SAMN04490355_101129 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.584 |
SFL61822.1 | lpxK | SAMN04490355_101113 | SAMN04490355_101117 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.642 |
SFL61838.1 | SFL61822.1 | SAMN04490355_101114 | SAMN04490355_101113 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 0.997 |
SFL61838.1 | SFL61908.1 | SAMN04490355_101114 | SAMN04490355_101118 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.924 |
SFL61838.1 | SFM02668.1 | SAMN04490355_101114 | SAMN04490355_10346 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Arabinose-5-phosphate isomerase. | 0.583 |
SFL61838.1 | kdsA | SAMN04490355_101114 | SAMN04490355_101115 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.988 |
SFL61838.1 | kdsB | SAMN04490355_101114 | SAMN04490355_101116 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.920 |
SFL61838.1 | lpxA | SAMN04490355_101114 | SAMN04490355_101122 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.891 |
SFL61838.1 | lpxB | SAMN04490355_101114 | SAMN04490355_101120 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.927 |
SFL61838.1 | lpxC | SAMN04490355_101114 | SAMN04490355_101124 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.918 |
SFL61838.1 | lpxD | SAMN04490355_101114 | SAMN04490355_101129 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.915 |
SFL61838.1 | lpxK | SAMN04490355_101114 | SAMN04490355_101117 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.922 |