STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCUnannotated protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1429 aa)    
Predicted Functional Partners:
dnaX
Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.891
dnaN
Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]
   
 0.888
holA
Unannotated protein.
    
 0.886
DXC78_08920
Unannotated protein.
    
0.886
DXC78_07825
Unannotated protein.
  
 0.883
rnc
Unannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.800
DXC78_03250
Unannotated protein; Belongs to the SEDS family.
     
 0.774
coaD
Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.769
rsmD
Unannotated protein.
  
    0.767
DXC78_01535
Unannotated protein.
  
     0.683
Your Current Organism:
Faecalicoccus pleomorphus
NCBI taxonomy Id: 1123313
Other names: F. pleomorphus DSM 20574, Faecalicoccus pleomorphus ATCC 29734, Faecalicoccus pleomorphus CCUG 11733, Faecalicoccus pleomorphus DSM 20574, Faecalicoccus pleomorphus LMG 17756, Streptococcus pleomorphus DSM 20574
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.