STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG89721.1Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. (213 aa)    
Predicted Functional Partners:
SHG89620.1
uroporphyrinogen-III synthase.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.994
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
  
 0.965
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.947
SHG89551.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.920
SHG89489.1
Transcriptional regulator, AsnC family.
 
  
  0.873
SHG89454.1
Transcriptional regulator, AsnC family.
 
  
  0.840
SHG89587.1
Radical SAM additional 4Fe4S-binding SPASM domain-containing protein.
 
     0.784
SHG89523.1
Putative heme d1 biosynthesis radical SAM protein NirJ2.
 
     0.728
SHH18897.1
Phosphoadenosine phosphosulfate reductase.
  
  
 0.607
Your Current Organism:
Thermosyntropha lipolytica
NCBI taxonomy Id: 1123382
Other names: T. lipolytica DSM 11003, Thermosyntropha lipolytica DSM 11003
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