STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SES74416.1Serine protease DegS. (359 aa)    
Predicted Functional Partners:
SET13166.1
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.959
SES73034.1
OmpA-OmpF porin, OOP family; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.951
SET56001.1
Hypothetical protein.
 
  
 0.828
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.710
SES71678.1
dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase.
   
 0.710
rsfS
Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
   0.695
SET27710.1
Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN metalloenzyme (JAMM) motif.
   
  0.690
SES65431.1
Chromosome segregation ATPase.
  
 
 0.628
SES95977.1
Phage shock protein C (PspC) family protein.
  
  
 0.608
SET35659.1
Catalase.
   
 0.603
Your Current Organism:
Thorsellia anophelis
NCBI taxonomy Id: 1123402
Other names: T. anophelis DSM 18579, Thorsellia anophelis DSM 18579
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