node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ42536.1 | SKA15510.1 | SAMN02745782_00243 | SAMN02745782_02622 | Aminomethyltransferase. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.469 |
SJZ42536.1 | folD | SAMN02745782_00243 | SAMN02745782_00842 | Aminomethyltransferase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.945 |
SJZ42536.1 | glyA | SAMN02745782_00243 | SAMN02745782_02896 | Aminomethyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.996 |
SJZ47237.1 | SKA15510.1 | SAMN02745782_00364 | SAMN02745782_02622 | Ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.404 |
SKA15501.1 | SKA15510.1 | SAMN02745782_02621 | SAMN02745782_02622 | Transposase. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.615 |
SKA15501.1 | SKA15520.1 | SAMN02745782_02621 | SAMN02745782_02623 | Transposase. | Acylphosphatase. | 0.431 |
SKA15510.1 | SJZ42536.1 | SAMN02745782_02622 | SAMN02745782_00243 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Aminomethyltransferase. | 0.469 |
SKA15510.1 | SJZ47237.1 | SAMN02745782_02622 | SAMN02745782_00364 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. | 0.404 |
SKA15510.1 | SKA15501.1 | SAMN02745782_02622 | SAMN02745782_02621 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Transposase. | 0.615 |
SKA15510.1 | SKA15520.1 | SAMN02745782_02622 | SAMN02745782_02623 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Acylphosphatase. | 0.608 |
SKA15510.1 | folD | SAMN02745782_02622 | SAMN02745782_00842 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.440 |
SKA15510.1 | glyA | SAMN02745782_02622 | SAMN02745782_02896 | 23S rRNA (cytosine1962-C5)-methyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.450 |
SKA15520.1 | SKA15501.1 | SAMN02745782_02623 | SAMN02745782_02621 | Acylphosphatase. | Transposase. | 0.431 |
SKA15520.1 | SKA15510.1 | SAMN02745782_02623 | SAMN02745782_02622 | Acylphosphatase. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.608 |
folD | SJZ42536.1 | SAMN02745782_00842 | SAMN02745782_00243 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Aminomethyltransferase. | 0.945 |
folD | SKA15510.1 | SAMN02745782_00842 | SAMN02745782_02622 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.440 |
folD | glyA | SAMN02745782_00842 | SAMN02745782_02896 | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |
glyA | SJZ42536.1 | SAMN02745782_02896 | SAMN02745782_00243 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminomethyltransferase. | 0.996 |
glyA | SKA15510.1 | SAMN02745782_02896 | SAMN02745782_02622 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 23S rRNA (cytosine1962-C5)-methyltransferase. | 0.450 |
glyA | folD | SAMN02745782_02896 | SAMN02745782_00842 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.943 |