STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGDemethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (229 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.969
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
     
 0.834
SFO84087.1
Methyltransferase domain-containing protein.
  
  
  0.799
SFP97437.1
Amino acid adenylation domain-containing protein.
    
 0.776
SFN98608.1
Hypothetical protein.
       0.768
SFQ73469.1
Methyltransferase domain-containing protein.
  
  
  0.755
SFN97983.1
Heptaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
  0.744
SFN98542.1
Geranylgeranyl reductase family.
    
 0.727
SFP60781.1
Amino acid adenylation domain-containing protein.
    
 0.713
SFQ70088.1
Ubiquinone/menaquinone biosynthesis C-methylase UbiE.
 
  
 
0.708
Your Current Organism:
Amycolatopsis rubida
NCBI taxonomy Id: 112413
Other names: A. rubida, Amycolatopsis rubida Huang et al. 2001, Amycolatopsis sp. 13.4, CIP 107102, DSM 44637, JCM 10871, NBRC 100041, NRRL B-24150, strain 13.4
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