STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO66590.1Two-component sensor histidine kinase, contains HisKA and HATPase domains. (506 aa)    
Predicted Functional Partners:
SFQ55936.1
Response regulator receiver and ANTAR domain protein.
 
   
 0.893
SFO03036.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.785
SFP18743.1
Thioredoxin reductase (NADPH).
    
 0.707
whiB-6
WhiB family transcriptional regulator, redox-sensing transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.694
whiB-4
WhiB family transcriptional regulator, redox-sensing transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.653
whiB-5
WhiB family transcriptional regulator, redox-sensing transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.651
SFP90200.1
Histidine kinase-like ATPase domain-containing protein.
    
 0.647
SFN99703.1
Hypothetical protein.
   
    0.645
SFO66621.1
RNA polymerase sigma-70 factor, ECF subfamily.
 
   
 0.633
SFO36119.1
PAS domain S-box-containing protein.
    
 0.632
Your Current Organism:
Amycolatopsis rubida
NCBI taxonomy Id: 112413
Other names: A. rubida, Amycolatopsis rubida Huang et al. 2001, Amycolatopsis sp. 13.4, CIP 107102, DSM 44637, JCM 10871, NBRC 100041, NRRL B-24150, strain 13.4
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