STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCF64373.1Putative Diadenosine tetraphosphate (Ap4A) hydrolase, HIT family hydrolases; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (193 aa)    
Predicted Functional Partners:
CCF64372.1
Putative phosphatidylinositol synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.942
pimA
Phosphatidylinositol alpha-mannosyltransferase; Function of strongly homologous gene; enzyme.
  
  
 0.928
cysD
Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.902
cysNC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
    
  0.902
cysD-2
Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.902
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
     
  0.900
CCF64371.1
Lipid A biosynthesis lauroyl acyltransferase; Function of strongly homologous gene; enzyme.
  
  
 0.886
CCF64369.1
Putative hydrolase, nudix family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Nudix hydrolase family.
       0.878
thrS-2
threonyl-tRNA synthetase; Function of strongly homologous gene; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.851
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
  0.607
Your Current Organism:
Nocardia cyriacigeorgica
NCBI taxonomy Id: 1127134
Other names: N. cyriacigeorgica GUH-2, Nocardia cyriacigeorgica GUH-2, Nocardia cyriacigeorgica str. GUH-2, Nocardia cyriacigeorgica strain GUH-2
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