gltT protein (Aliiglaciecola lipolytica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

gltT

Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (454 aa)

Predicted Functional Partners:

GLIP_0990

0.670

sdhD

0.633

GLIP_3247

0.631

GLIP_2261

0.575

GLIP_0631

0.566

udk

0.544

GLIP_0287

0.537

GLIP_2186

0.537

GLIP_2811

0.534

GLIP_4360

0.522

Your Current Organism:

Aliiglaciecola lipolytica

NCBI taxonomy Id: 1127673
Other names: A. lipolytica E3, Aliiglaciecola lipolytica E3, Glaciecola lipolytica E3, marine bacterium E3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLIP_0287	GLIP_0631	GLIP_0287	GLIP_0631	Multidomain protein; Contains Na+/proline symporter PutP-like domain, sensory histidine kinase and receiver domain.	Hypothetical protein.	0.508
GLIP_0287	gltT	GLIP_0287	GLIP_2262	Multidomain protein; Contains Na+/proline symporter PutP-like domain, sensory histidine kinase and receiver domain.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.537
GLIP_0631	GLIP_0287	GLIP_0631	GLIP_0287	Hypothetical protein.	Multidomain protein; Contains Na+/proline symporter PutP-like domain, sensory histidine kinase and receiver domain.	0.508
GLIP_0631	GLIP_0990	GLIP_0631	GLIP_0990	Hypothetical protein.	Small GTP-binding protein.	0.988
GLIP_0631	gltT	GLIP_0631	GLIP_2262	Hypothetical protein.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.566
GLIP_0631	udk	GLIP_0631	GLIP_2808	Hypothetical protein.	Uridine kinase.	0.773
GLIP_0990	GLIP_0631	GLIP_0990	GLIP_0631	Small GTP-binding protein.	Hypothetical protein.	0.988
GLIP_0990	GLIP_2811	GLIP_0990	GLIP_2811	Small GTP-binding protein.	Hypothetical protein.	0.685
GLIP_0990	gltT	GLIP_0990	GLIP_2262	Small GTP-binding protein.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.670
GLIP_0990	udk	GLIP_0990	GLIP_2808	Small GTP-binding protein.	Uridine kinase.	0.818
GLIP_2186	gltT	GLIP_2186	GLIP_2262	neurotransmitter:Na+ symporter, NSS family.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.537
GLIP_2261	gltT	GLIP_2261	GLIP_2262	Invasin domain protein.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.575
GLIP_2811	GLIP_0990	GLIP_2811	GLIP_0990	Hypothetical protein.	Small GTP-binding protein.	0.685
GLIP_2811	GLIP_3247	GLIP_2811	GLIP_3247	Hypothetical protein.	B12-dependent methionine synthase.	0.553
GLIP_2811	gltT	GLIP_2811	GLIP_2262	Hypothetical protein.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.534
GLIP_2811	udk	GLIP_2811	GLIP_2808	Hypothetical protein.	Uridine kinase.	0.594
GLIP_3247	GLIP_2811	GLIP_3247	GLIP_2811	B12-dependent methionine synthase.	Hypothetical protein.	0.553
GLIP_3247	gltT	GLIP_3247	GLIP_2262	B12-dependent methionine synthase.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.631
GLIP_3247	udk	GLIP_3247	GLIP_2808	B12-dependent methionine synthase.	Uridine kinase.	0.620
GLIP_4360	gltT	GLIP_4360	GLIP_2262	Sodium-dependent symporter family protein.	Proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	0.522

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Network Stats

number of nodes:

4

number of edges:

3

average node degree:

1.5

avg. local clustering coefficient:

0.75

expected number of edges:

3

PPI enrichment p-value:

0.565

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 102

1.23

1.92

4.54e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 52

1.48

2.81

8.10e-12

GO:0019843

rRNA binding

6 of 38

1.39

1.66

1.24e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 56

1.45

2.73

3.42e-12

GO:0015934

Large ribosomal subunit

2 of 8

1.59

0.8

0.0233

GO:0005622

Intracellular anatomical structure

11 of 594

0.46

0.4

0.00015

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:133

Ribosome

10 of 49

1.51

3.0

1.12e-12

CL:135

Structural constituent of ribosome

9 of 41

1.54

2.99

1.14e-11

CL:138

rRNA-binding

5 of 10

1.89

2.93

1.91e-07

CL:137

Structural constituent of ribosome

6 of 20

1.67

2.7

5.27e-08

CL:124

Ribosome, and Translation regulator activity

11 of 75

1.36

2.48

7.78e-13

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 54

1.46

2.81

2.22e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 46

1.49

2.67

1.70e-10

GOCC:0015934

Large ribosomal subunit

5 of 14

1.75

2.44

1.30e-06

GOCC:0044391

Ribosomal subunit

6 of 25

1.58

2.29

4.18e-07

GOCC:0022625

Cytosolic large ribosomal subunit

4 of 12

1.72

1.97

3.03e-05

GOCC:0022626

Cytosolic ribosome

5 of 22

1.55

1.96

6.61e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 54

1.46

2.78

3.98e-12

KW-0699

rRNA-binding

6 of 37

1.41

1.78

3.73e-06

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