STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoE-8RNA polymerase sigma-70 factor, ECF subfamily. (204 aa)    
Predicted Functional Partners:
GLIP_3271
Transcription negative regulator ChrR.
 
 
 0.977
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.780
GLIP_1031
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.726
GLIP_3273
Hypothetical protein.
 
   
 0.719
rpoE-3
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.718
rpoE-5
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.695
GLIP_3276
Hypothetical protein.
 
     0.674
rpoE-9
RNA polymerase sigma-70 factor, ECF subfamily.
  
     0.641
GLIP_3275
Conserved hypothetical protein.
 
    0.632
rpoE-4
RNA polymerase sigma-70 factor, ECF subfamily.
  
     0.631
Your Current Organism:
Aliiglaciecola lipolytica
NCBI taxonomy Id: 1127673
Other names: A. lipolytica E3, Aliiglaciecola lipolytica E3, Glaciecola lipolytica E3, marine bacterium E3
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