Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (315 aa)    
Predicted Functional Partners:
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.862
EKX96451.1
Polyprenyl synthetase; KEGG: pmz:HMPREF0659_A5037 5.7e-110 polyprenyl synthetase; K02523 octaprenyl diphosphate synthase; Psort location: Cytoplasmic, score: 9.97.
    
 0.851
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.814
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.775
EKY04295.1
HD domain protein; Psort location: Cytoplasmic, score: 8.96.
  
    0.663
EKX99206.1
Isochorismate synthase; KEGG: pru:PRU_1686 2.1e-71 menF; menaquinone-specific isochorismate synthase K02361.
 
   
 0.584
EKX99202.1
Hypothetical protein; KEGG: pmz:HMPREF0659_A6053 4.2e-91 hypothetical protein; K01911 O-succinylbenzoic acid--CoA ligase; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.581
EKX99207.1
Hypothetical protein; KEGG: aha:AHA_2647 2.1e-16 esterase YdiI.
 
  
 0.530
EKY03919.1
Methyltransferase domain protein; KEGG: rha:RHA1_ro03827 1.4e-10 ubiquinone/menaquinone methyltransferase K03183; Psort location: Cytoplasmic, score: 8.96.
    
 0.502
EKX99203.1
O-succinylbenzoate synthase; KEGG: pru:PRU_1683 3.1e-111 menC; O-succinylbenzoic acid synthetase K02549; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.470
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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