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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (501 aa)    
Predicted Functional Partners:
EKY03862.1
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.992
EKY03863.1
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.990
EKY03864.1
KEGG: pru:PRU_0732 7.3e-213 (R)-citramalate synthase; K09011 D-citramalate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 
0.952
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.951
EKY03451.1
KEGG: pru:PRU_0166 4.1e-155 ilvE; branched-chain-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 9.26.
  
 0.941
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.941
EKX97318.1
Acetolactate synthase, small subunit.
 
 
 0.937
EKY03884.1
Pyruvate synthase; KEGG: pmz:HMPREF0659_A5561 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.930
EKX97317.1
Acetolactate synthase, large subunit.
 
 
 0.922
EKY00506.1
AMP-binding enzyme; KEGG: pru:PRU_2205 2.1e-238 AMP-binding enzyme; K01895 acetyl-CoA synthetase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.856
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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