Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY03862.13-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (464 aa)    
Predicted Functional Partners:
EKY03863.1
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.999
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.999
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.992
EKY03864.1
KEGG: pru:PRU_0732 7.3e-213 (R)-citramalate synthase; K09011 D-citramalate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.985
EKY03884.1
Pyruvate synthase; KEGG: pmz:HMPREF0659_A5561 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
   
 0.906
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.846
EKX97318.1
Acetolactate synthase, small subunit.
  
  
 0.830
EKX98504.1
Pyruvate kinase; KEGG: pmz:HMPREF0659_A6470 1.5e-189 pyk; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
EKX97285.1
Formate C-acetyltransferase.
     
  0.829
EKX97320.1
Ketol-acid reductoisomerase.
  
  
 0.819
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.