| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKX99490.1 | dacA | HMPREF9151_01686 | HMPREF9151_00273 | KEGG: bfr:BF1478 8.6e-242 phosphoglucomutase phosphomannomutase; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 8.96. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.750 |
| EKX99611.1 | EKY00022.1 | HMPREF9151_01631 | HMPREF9151_01422 | YbbR-like protein; Psort location: Cytoplasmic, score: 8.96. | 7TM receptor with intracellular HD hydrolase; KEGG: bmd:BMD_4538 2.4e-63 metal-dependent phosphohydrolase K07037; Psort location: CytoplasmicMembrane, score: 10.00. | 0.744 |
| EKX99611.1 | dacA | HMPREF9151_01631 | HMPREF9151_00273 | YbbR-like protein; Psort location: Cytoplasmic, score: 8.96. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.621 |
| EKY00022.1 | EKX99611.1 | HMPREF9151_01422 | HMPREF9151_01631 | 7TM receptor with intracellular HD hydrolase; KEGG: bmd:BMD_4538 2.4e-63 metal-dependent phosphohydrolase K07037; Psort location: CytoplasmicMembrane, score: 10.00. | YbbR-like protein; Psort location: Cytoplasmic, score: 8.96. | 0.744 |
| EKY00022.1 | dacA | HMPREF9151_01422 | HMPREF9151_00273 | 7TM receptor with intracellular HD hydrolase; KEGG: bmd:BMD_4538 2.4e-63 metal-dependent phosphohydrolase K07037; Psort location: CytoplasmicMembrane, score: 10.00. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.492 |
| EKY02367.1 | dacA | HMPREF9151_00811 | HMPREF9151_00273 | Phosphoglucosamine mutase; KEGG: pmz:HMPREF0659_A5955 8.9e-192 glmM; phosphoglucosamine mutase; Psort location: Cytoplasmic, score: 9.97. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.750 |
| EKY03632.1 | EKY03633.1 | HMPREF9151_00274 | HMPREF9151_00275 | KEGG: pru:PRU_2262 1.4e-83 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 9.97. | Antioxidant, AhpC/TSA family; KEGG: bay:RBAM_021290 5.0e-15 resA; thiol-disulfide oxidoreductase; Psort location: CytoplasmicMembrane, score: 7.88. | 0.773 |
| EKY03632.1 | dacA | HMPREF9151_00274 | HMPREF9151_00273 | KEGG: pru:PRU_2262 1.4e-83 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 9.97. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.740 |
| EKY03633.1 | EKY03632.1 | HMPREF9151_00275 | HMPREF9151_00274 | Antioxidant, AhpC/TSA family; KEGG: bay:RBAM_021290 5.0e-15 resA; thiol-disulfide oxidoreductase; Psort location: CytoplasmicMembrane, score: 7.88. | KEGG: pru:PRU_2262 1.4e-83 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 9.97. | 0.773 |
| EKY03633.1 | dacA | HMPREF9151_00275 | HMPREF9151_00273 | Antioxidant, AhpC/TSA family; KEGG: bay:RBAM_021290 5.0e-15 resA; thiol-disulfide oxidoreductase; Psort location: CytoplasmicMembrane, score: 7.88. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.658 |
| dacA | EKX99490.1 | HMPREF9151_00273 | HMPREF9151_01686 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: bfr:BF1478 8.6e-242 phosphoglucomutase phosphomannomutase; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 8.96. | 0.750 |
| dacA | EKX99611.1 | HMPREF9151_00273 | HMPREF9151_01631 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | YbbR-like protein; Psort location: Cytoplasmic, score: 8.96. | 0.621 |
| dacA | EKY00022.1 | HMPREF9151_00273 | HMPREF9151_01422 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 7TM receptor with intracellular HD hydrolase; KEGG: bmd:BMD_4538 2.4e-63 metal-dependent phosphohydrolase K07037; Psort location: CytoplasmicMembrane, score: 10.00. | 0.492 |
| dacA | EKY02367.1 | HMPREF9151_00273 | HMPREF9151_00811 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucosamine mutase; KEGG: pmz:HMPREF0659_A5955 8.9e-192 glmM; phosphoglucosamine mutase; Psort location: Cytoplasmic, score: 9.97. | 0.750 |
| dacA | EKY03632.1 | HMPREF9151_00273 | HMPREF9151_00274 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: pru:PRU_2262 1.4e-83 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 9.97. | 0.740 |
| dacA | EKY03633.1 | HMPREF9151_00273 | HMPREF9151_00275 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Antioxidant, AhpC/TSA family; KEGG: bay:RBAM_021290 5.0e-15 resA; thiol-disulfide oxidoreductase; Psort location: CytoplasmicMembrane, score: 7.88. | 0.658 |
| dacA | murF | HMPREF9151_00273 | HMPREF9151_00106 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.400 |
| dacA | mutS2 | HMPREF9151_00273 | HMPREF9151_01919 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.544 |
| dacA | nnrD | HMPREF9151_00273 | HMPREF9151_02605 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.442 |
| murF | dacA | HMPREF9151_00106 | HMPREF9151_00273 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.400 |