STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY03131.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (410 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
  
 0.899
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
 
 0.895
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
 
 0.891
EKY02905.1
Aminotransferase, class I/II; KEGG: pru:PRU_1300 5.1e-196 putative aspartate aminotransferase; K00811 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
  0.862
EKX98752.1
Putative aspartate transaminase; KEGG: pru:PRU_1914 5.5e-176 aatA; aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 9.97.
  
  0.862
EKY00061.1
Putative pantothenate kinase; KEGG: pmz:HMPREF0659_A6904 8.0e-104 putative pantothenate kinase; K09680 type II pantothenate kinase.
     
 0.844
EKY01219.1
Cysteine synthase A; KEGG: pmz:HMPREF0659_A6111 1.8e-131 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.842
EKX98783.1
KEGG: pmz:HMPREF0659_A5992 1.2e-166 putative cystathionine beta-lyase PatB; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 9.97.
     
  0.829
EKY03130.1
Exonuclease; KEGG: pmz:HMPREF0659_A5674 1.5e-109 exonuclease; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96.
  
    0.784
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.733
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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