STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY03086.1Sigma-70 region 2; KEGG: reh:H16_A2563 2.7e-16 rpoE1; RNA polymerase sigma factor RpoE K03088; Psort location: Cytoplasmic, score: 9.26; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)    
Predicted Functional Partners:
EKY03085.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.825
EKY03087.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.825
EKY02028.1
Sigma-70 region 2; KEGG: bpu:BPUM_0902 5.4e-11 sigM; RNA polymerase sigma factor SigM K03088; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.763
EKY02104.1
Sigma-70 region 2; KEGG: ctu:Ctu_31640 2.5e-09 rpoE; RNA polymerase sigma factor RpoE K03088; Psort location: Cytoplasmic, score: 9.26; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.760
EKX98341.1
Sigma-70 region 2; KEGG: reh:H16_A2563 2.4e-15 rpoE1; RNA polymerase sigma factor RpoE K03088; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.756
EKY03082.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.652
EKY03084.1
KEGG: spn:SP_1402 1.7e-53 NOL1/NOP2/sun family protein; K00599; Psort location: Cytoplasmic, score: 9.26.
       0.652
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.650
EKY02991.1
RNA polymerase sigma-70 factor; KEGG: chu:CHU_3562 1.1e-14 rpoE; ECF subfamily RNA polymerase sigma factor K03088; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.549
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.541
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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