Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKY02885.1Exodeoxyribonuclease III; KEGG: pmz:HMPREF0659_A5467 3.3e-114 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97. (249 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
 0.985
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.822
EKY03129.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.813
EKX97338.1
Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.799
EKY02886.1
Hypothetical protein.
       0.795
EKX98605.1
Pseudouridylate synthase; KEGG: pmz:HMPREF0659_A6154 1.8e-186 pseudouridylate synthase; K06178 ribosomal large subunit pseudouridine synthase B; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family.
  
    0.676
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.660
hisB
Histidinol-phosphatase; KEGG: pru:PRU_0455 4.1e-148 hisB; histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase K01089; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
   
 
 0.630
folE
GTP cyclohydrolase I; KEGG: pru:PRU_1862 2.9e-83 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 9.97.
       0.617
EKY02888.1
Sporulation and cell division repeat protein.
       0.517
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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