STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EKY02824.1Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (549 aa)    
Predicted Functional Partners:
EKX96355.1
KEGG: pmz:HMPREF0659_A5048 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.996
EKY01994.1
Lactate/malate dehydrogenase, NAD binding domain protein; KEGG: pgi:PG1949 3.8e-129 mdh; malate dehydrogenase; K00024 malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.994
EKX96357.1
KEGG: pmz:HMPREF0659_A5049 9.4e-117 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.984
EKX99565.1
KEGG: pmz:HMPREF0659_A6863 0. malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.979
EKX96211.1
KEGG: pru:PRU_2260 6.9e-137 pta; phosphate acetyltransferase K00625; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.928
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.927
argH
Argininosuccinate lyase; KEGG: pru:PRU_2393 5.1e-189 argH; argininosuccinate lyase K01755; Psort location: Cytoplasmic, score: 9.97.
    
 0.907
EKX96354.1
KEGG: pmz:HMPREF0659_A5047 1.2e-100 succinate dehydrogenase cytochrome b subunit, b558 family; K00241 succinate dehydrogenase cytochrome b-556 subunit; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.899
EKX96860.1
FAH family protein; KEGG: chu:CHU_1891 2.6e-50 ycgM; 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase K01828; Psort location: Cytoplasmic, score: 9.97.
     
  0.884
EKY02966.1
KEGG: bfs:BF3716 5.9e-147 putative aminotransferase; K00837; Psort location: Cytoplasmic, score: 9.97.
    
  0.882
Your Current Organism:
Prevotella saccharolytica
NCBI taxonomy Id: 1127699
Other names: P. saccharolytica F0055, Prevotella saccharolytica F0055, Prevotella saccharolytica str. F0055, Prevotella saccharolytica strain F0055
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